TOP5 MONTHLY FAVORITES FEB 2021
1. SHISEIDO SEA BREEZE NATURAL+ AID RINSE IN SHAMPOO 600ml
💡DETAILS: Recommended for Sun-damaged hair + Dirty, greasy scalp, to clean and refresh + Cool and refreshing sensation + Oily hair, for light, clean hair
🔴MY REVIEW: I would definitely recommend this shampoo. It doesn’t seem to leave any residue behind or make my hair feel weighed down, my hair feels clean and light. So far I really like it. This one is just what I need. Not too strong, yet refreshing. I totally recommend.
2. VS SEA WATER SPRAY 100ml
💡DETAILS: [Allow hair to create root lift and volume] Create texturized voluminous style for soft and limp hair.
🔴MY REVIEW: I love this hair spray so much. I’ve used it twice and immediately saw a big difference in the fullness of my hair. This also leaves my hair soft and not stiff like other volumizers. I highly recommend it to add volume to your hair.
3. HADATUKO WHITENING FACE AND NECK 3D MASK 5 PIECES BOX
💡DETAILS: Hadatuko Whitening Face and Neck 3D Mask help you achieve white, flawless, glow and clear skin. The formula contain whitening ingredients including SymWhite 377, Arbutin, Cherry seed extract, Raspberry extract and Rose seed extract. It inhibits melanocytes to whitening your skin. It is anti-oxidizing and replenishes moisture to your skin. In addition with the Japanese nano technology and 3D fit cutting, essence can quickly penetrate into the bottom part of the skin and provide nourishment.
🔴MY REVIEW: Normally my skin gets very dry in Spring season and I’m really looking forward to trying some sheet masks that can moisturize my skin. This 3D mask works great, very hydrating and soothing for my skin. It really made my skin feel super soft, no issues with my sensitivity either. This sheet mask clung closely to my skin to facilitate the absorption of the serum. I only used 5 sheet masks so far and I got good results on my skin. Well, I was always concerned that the fine lines on my neck would get more and more obvious. The 3D mask solves my problem and I truly believe if I apply it regularly I can avoid or at least postpone the formation of the wrinkles on my face and neck. Definitely recommend.
4. LONKOOM ESSENTIAL OILS SET [LAVENDER + LEMONGRASS + TEA TREE + PEPPERMINT + SWEET ORANGE + EUCALYPTUS] 6 * 10ml
💡DETAILS: [100% Pure Essential Oils] [TEA TREE] Its powerful antiseptic properties wipe out harmful beacteria to heal wounds quickly and prevent future infection. When applied to the body,it creates a cooling sensation that wakes up dull,dehydrated skin and leaves you feeling completely refreshed. [SWEET ORANGE] The rich component d-limonene aids in maintaining normal cellular regeneration and gives off a natural,calming effect. A sweet cocktail for the senses, this aroma promotes positive attitudes and induces relaxation for a calm spirit. [PEPPERMINT] It is a great for many health restorative properties. It is used as a medicinal and calming aroma to treat a wide variety of bodily organs. It can be helpful in calming gastrointestinal issues,reducing muscle pain and relieving anxiety. [LAVENDER] it is the essense of pure calmness and relaxation. This versatile oil gives off a light scent,which uplifts the spirit while transitioning moods to the ultimate state of calmness. [LEMONGRASS] A great herb for inducing relaxation and balance for the mind. Externally, it helps relieves muscle pain and aches,as well as kill harmful bacteria. [EUCALYPTUS] Known for its awesome ability to improve respiratory issues(such as that pesky common cold),it can clear out that cough and heavy congestion we all have suffered from.
🔴MY REVIEW: Very nice to find a set with a good variety. Every scent is unique and my favorite is peppermint. They are 100% Pure Essential Oils. This set comes in a very nice packaging and includes oils of sweet orange, peppermint, lavender, lemongrass, tea tree and eucalyptus and an enclosed leaflet which gives a details and instruction about uses and benefits of all these oils. This set of essential oils are really nice. I would recommend these.
5. UTICARE 30pcs
💡DETAILS: Improves ecosystem of your V + Reduces incidence of recurrence + Maintains beneficial bacteria + Restores protective barrier
🔴MY REVIEW: There are "good bacteria" and "bad bacteria" in the human body. Killing all the bacteria is actually just self-defeating. However, this product has been verified by both Japanese and Hong Kong notary companies, and the data proves that it is very important to kill 99% of private evil bacteria (such as Candida and E. coli) in 24 hours while retaining good bacteria. During COVID-19 , I really don’t want to go to the clinic or hospital because of any illness. Highly recommend this product [Uticare] to improve the ecology of the private bacterial flora.
📌Disclaimer: The above review is purely personal opinion. Not everyone likes what I like. Please note that what may work for me, may not work for anyone else. Results may vary from person to person, so please take this into consideration if you decide to try those products.
🔎WEBSITE - https://www.seabreezeweb.com
🔎WEBSITE - http://www.toolsofsassoon.com.hk/mavista/cms/en/home
🔎FACEBOOK - https://www.facebook.com/VidalSassoon/
🔎IG - @vs_sassoon_hk
🔎WEBSITE - https://www.sasa.com.hk
🔎FACEBOOK - https://www.facebook.com/sasahongkong/
🔎IG - @sasahk_official
🔎WEBSITE - https://www.amazon.com/
🔎FACEBOOK - https://www.facebook.com/Amazon/
🔎IG - @amazon
🔎WEBSITE - https://www.uticare.com.hk
🔎FACEBOOK - https://www.facebook.com/uticare
🔎IG - @uticarehk
#shiseido #seabreeze #vidalsassoon #hadatuko #amazon #lonkoom #uticare #top5 #monthlyfavorites #beautyblogger #kakablogs #kakalovekakalovelife #productreview #shoponline
同時也有1部Youtube影片,追蹤數超過83萬的網紅serpentza,也在其Youtube影片中提到,If you're coming to China, be it for work or pleasure, there are three glaringly big and not often talked about health risks/issues that you should be...
aids infection 在 藥學人生 - Pharmalife Facebook 的最讚貼文
2020年 HIV 單錠處方 (single tablet regimen; STR) 小整理
———————————————
更正:Dovato 於 GEMINI study 中,因藥物不良反應而停藥的比例應為 2.1%,原版本 (2020.12.16) 誤植為 0.3% 是我的疏失,非常抱歉。
———————————————
今年台灣愛滋病學會治療指引的表格設計的很棒,我也想更新一下這份表格,複習知識延續熱忱之外,也希望能提供給在這個領域工作的夥伴們做參考。
另存圖片後的解析度會很悲劇,請點選以下連結下載您需要的格式:
☞ 表格下載 (PNG):http://bit.ly/382Df7u
☞ 表格下載 (PDF):http://bit.ly/3r04uZb
本篇為臉書簡潔扼要版 (?),詳細內容請見此連結:http://bit.ly/2Wkwrg7
🛫 在 COVID-19 全球肆虐的時代,如果 HIV 病友有需要出國,請務必要把抗病毒藥帶足帶滿,特別是 HIV/HBV coinfection 的病友,更是務必要好好保重。
———————————————
在照顧 HIV 病友的醫療團隊、台灣愛滋病學會、各個 NGO,還有政府,以及藥廠的持續努力下,「90-90-90」的指標,我們不斷進步:從 2019 年達到了「87-90-94」,2020 年我們更進一步達成「90-92-95」,這樣的成績是令人振奮的,能成為照護團隊的一員並為此貢獻一點心力,我覺得既幸運又榮幸(雖然去年就說過這句話,但今年還是一樣的心情 ^^)。
HIV 抗反轉錄病毒藥以單錠處方 (single tablet regimen; STR) 的形態降臨後,大幅的增加病友的服藥方便性、順從性,也增加了醫師開藥的簡便性,更讓藥師可以瀟灑快意的調配藥品 (燦笑),可以說 STR 的普及,創造了三贏的局面!
☑ 2020 年 3 月,滋若愷 Juluca (DTG/RPV) 加入了治療的行列;2020 年 12 月,洛瓦梭 Dovato (DTG/3TC) 以及達滋克 Delstrigo (TDF/3TC/DOR) 也加入了處方使用規範的第一線推薦處方中。
———————————————
👍 滋若愷 Juluca (DTG/RPV)
☑ 僅作為「當病毒量達到穩定控制後之處方轉換 (stable-switch)」
☑ 不適合治療 HBV/HIV coinfection:Juluca 為雙藥處方 (2 drug regimen; 2DR),且不含有任何能治療 HBV 感染的成份,請別用來治療本身具有 B 型肝炎帶原的 HIV 病友。
☑ 隨餐服用、謹慎注意並服的胃藥是否具有交互作用:Juluca 含有 rilpivirine (RPV),應隨餐服用,雖然仿單沒寫當次餐點的建議熱量,但基於 Complera 的資料,建議當次餐點熱量仍應大於 390 kCal。併用 PPI 為 RPV 的使用禁忌,與 H2 blocker 或制酸劑也須錯開一定的時間才能使用,請特別注意這方面的交互作用。
☑ Juluca 為腎病者的友善用藥:雖然 Juluca 仿單顯示其於 CrCl <30 mL/min 之腎功能障礙者的使用經驗較少,但根據藥動學資料,DTG 與 RPV 於腎功能障礙者,應該都不需要調整劑量。
☑ 體重增加是嵌合酶抑制劑 (InSTi) 使用者常被觀察到的狀況,但其機轉仍未明瞭,而且其造成的體重增加對身體究竟是好事壞仍有待釐清。此外,如經過飲食控制與生活習慣調整,體重增加的趨勢可望趨緩。
✨ ✨ ✨ ✨ ✨ ✨ ✨ ✨ ✨
若病友服用抗病毒藥一段時間後,出現體重增加或其他副作用並為此困擾,請與你所屬的醫療團隊討論對策,絕對不要隨便停藥,好好壓制病毒才能好好保護你自己!
✨ ✨ ✨ ✨ ✨ ✨ ✨ ✨ ✨
👍 洛瓦梭 Dovato (DTG/3TC)
☑ 第一個被核准用於治療 HIV 新診斷病人的 2DR STR,但目前還是有「不建議用於病毒量超過50萬 copies/mL」的使用限制。一般認為,Dovato 的抗藥屏障 (genetic barrier) 不亞於 Triumeq,非常強效。
☑ 不建議用於 HIV/HBV coinfection:Dovato 雖然有 3TC 可以壓制 HBV,但過往的資料顯示,單用 3TC 治療一段時間後,HBV 較容易對其產生抗藥性。因此若是同時合併 HIV/HBV 感染,仍舊建議使用含有 tenofovir 的處方。
☑ Dovato 是揮別傷心,只剩清純的天使版 Triumeq:相較於 Triumeq (ABC/3TC/DTG),Dovata 不含 abacavir (ABC),因此比較沒有心毒性的長期疑慮。對於本身有心血管病史、年齡較長的感染者而言,是相對友善的選擇。
☑ Dovato 併用 rifapentine 的安全性仍有待商榷:個人認為 Triumeq 與 rifapentine 的資料,未必能完全沿用到 Dovato 上,或許可以等後續臨床研究出爐再做評估。
👍 達滋克 Delstrigo (TDF/3TC/DOR)
☑ 空腹、隨餐都可以的新一代 nNRTI STR:doravirine (DOR) 為新一代 nNRTI,藥品吸收不受食物影響,適合看心情吃早餐 (?) 的人。但也由於是 nNRTI,因此相較於第二代 InSTi (Biktarvy, Triumeq, Dovato) 與蛋白酶抑制劑 Symtuza 而言,Delstrigo 的抗藥屏障 (genetic barrier) 是偏低。
☑ Delstrigo 搭載 TDF,CrCl <50 mL/min 者不建議使用;並需注意長期腎功能與骨密度變化。
☑ 不建議與代謝酵素誘導劑 (CYP3A4 inducer) 併用:DOR 主要經由 CYP3A4 代謝,因此有使用 carbamazepine, phenytoin, oxcarbazepine, phenobarbital, rifampin 或 rifapentine 等 CYP3A4 inducer 之感染者,不建議使用 Delstrigo。
☑ 臨床試驗顯示,使用 Delstrigo 者似乎不會有體重增加的問題,這點倒是與 rilpivirine 相當(不過如果天天搭雞排配 Odefsey 應該還是會胖啦...)。
👍 信澤力 Symtuza (TAF/FTC/DRV/C)
☑ 需隨餐使用的 PI STR,擁有相當高的抗藥屏障:可作為其他第一線治療失敗後的救援治療;對於使用 pre-exposure prophylaxis (PrEP) 失敗而感染 HIV 的 B 型肝炎帶原者,Symtuza 是推薦的選擇。
☑ 交互作用很複雜:有 darunavir (DRV) 又有 cobicistat,交互作用既多且雜。
👍 吉他韋 Biktarvy (TAF/FTC/BIC)
☑ Biktarvy 可以同時治療 HIV/HBV infection,對肝腎功能障礙族群的泛用性較高,交互作用較少,副作用輕微,長期安全性佳,更有著比肩於 Triumeq 的超高抗藥屏障,而且不用衛教要不要隨餐服用 (開心),可說是幾乎符合 "Same-Day Antiretroviral Therapy" 條件的好藥。
☑ Biktarvy 可以說是沒什麼死角,除了需要特別閃 rifampin, rifapentine 之外,大概可以討論的就只剩體重增加的問題,但坦白說此影響究竟是好是壞目前仍沒有定論,因此仍要強調「若擔憂體重增加,請與醫療團隊討論,不要擅自停藥」。
👍 安以斯 Odefsey (TAF/FTC/RPV)
☑ 安全有效,但不建議用於病毒量 >10 萬 copies/mL 者:Odefsey 是對腎功能與骨質健康更友善的 TAF 版 Complera,對於需要使用抗病毒藥物長期治療的個案,是更理想的選擇。
☑ 隨餐服用、謹慎注意並服的胃藥是否具有交互作用。
☑ 抗藥屏障較低,也同樣很怕代謝酵素誘導劑。
👍 三恩美 Triumeq (ABC/3TC/DTG)
☑ 制霸過去四年的王者:夠強效,無視病毒量;抗藥屏障超高;空腹隨餐都可以吃;不干擾 HCV DAA;超級大一粒(幸好可以剝半、磨粉)。
☑ 心毒性疑慮:洋人資料顯示,長期使用 abacavir (ABC) 可能會增加缺血性心臟病風險。
☑ Triumeq 也具有體重增加的疑慮,我強調第三次:「若擔憂體重增加,請與醫療團隊討論,不要擅自停藥」
☑ 不建議用於 HIV/HBV coinfection。
☑ 當與 rifampin 併用時,應審慎調整 Triumeq 與 DTG 的劑量。
———————————————
☑ HIV STR vs. HCV DAA使用 Maviret 者,請避免使用 Atripla 或 Symtuza。使用 Epclusa 者,請避免使用 Atripla。使用含有 sofosbuvir 成分之 DAA (Harvoni, Epclusa) 者,若併用含有 TDF 成分之 ART (Atripla, Delstrigo),應謹慎監測腎功能變化。
☑ 治療 HIV/TB coinfection 時,與 rifampin 的交互作用始終是讓人困擾的問題:Atripla 仍舊是最方便百搭的選擇;Triumeq 或 Dovato 則需額外加一顆 dolutegravir 並錯開服用(個人認為 Dovato 的資料還是偏少的);其餘的 Odefsey, Delstrigo, Genvoya, Biktarvy, Symtuza, Juluca 則不建議與 rifampin 一起使用。
☑ 針對具有潛伏 TB 感染 (LTBI) 的 HIV 感染者,9H 或 3HP 是最常用的治療處方,其中方便又有效的 3HP 因含有 rifapentine,可能會降低 Atripla 以外的 HIV STR 之療效,出手前宜審慎評估;而基於 DOLPHIN trial 的研究結果,使用 Triumeq 者,當其病毒量達到穩定控制時,始可考慮使用 3HP。而 Dovato 與 3HP 搭配的安全性,個人認為仍須累積更多實證資料以做參酌。
———————————————
製表與整理:亞東紀念醫院感染科 HIV 照護團隊
———————————————
感謝:亞東紀念醫院感染科、HIV個管師團隊、藥學部
特別感謝楊家瑞醫師的指導和鼓勵
感謝台灣愛滋病學會與各大藥廠舉辦相關研討會,讓我們醫療人員可以更精進專業能力,提供給病友更好的照顧品質
#HIV #AIDS #亞東醫院 #ART #ARV #antiretroviral #SingleTabletRegimen #STR #IDPharmacist #科學能幫助瞭解真相 #同理心可以減少歧視
aids infection 在 Focus Taiwan Facebook 的最佳貼文
The number of reported #HIV infections reached a peak at 3,377 in 2005 but has been declining due to joint efforts by various government agencies to curb the spread of infection, the health minister said, citing statistics compiled by the Centers for Disease Control #CDC ahead of Dec. 1 #WorldAIDSDay.
https://focustaiwan.tw/society/202011290011
aids infection 在 serpentza Youtube 的最讚貼文
If you're coming to China, be it for work or pleasure, there are three glaringly big and not often talked about health risks/issues that you should be aware of.
Sasha's channel: https://www.youtube.com/channel/UCXFUJBn-uVw7NuBcDu-byFw
Smoking article:
http://www.wpro.who.int/china/mediacentre/releases/2017/20170414-tobacco-report/en/
Diabetes article: http://www.wpro.who.int/china/mediacentre/releases/2016/20160406/en/
Support Sasha and I on Patreon: http://www.patreon.com/serpentza
Join me on Facebook: http://www.facebook.com/winstoninchina
Twitter: @serpentza
Instagram: serpent_za
My other channel: https://www.youtube.com/c/advchina
Music used: Virtual Vice - Kowloon City 2010
Artist's bandcamp: https://new-world.bandcamp.com/album/off-duty