PRODUCTS REVIEW - MOIA ELIXIRS
1. N°37 30ml
💡DETAILS: [Dropper bottle: CBD Raspberry Seed Oil, Sandalwood Essential] Raspberry oil with CBD is a very effective natural cosmetic product that is quickly absorbed, supports skin regeneration and protects against oxidative stress. Hydrates and revitalizes the skin. It removes pores of impurities and dead cells. It contains sandalwood, which helps to concentrate and harmonizes during emotional stress. It can be used as a tonic for hair nutrition or in the bath as aromatherapy.
🔴MY REVIEW: MOIA ELIXIRS N°37 with CBD formula can also be used as a daily hair care oil. Using it on my scalp, my scalp is healthier than before. In addition to protecting the skin, this product can also help keep the scalp healthy. Using one to two drops each time can effectively calm my scalp and keep my hair shiny without frizzy feeling. Highly recommend.
2. N°01 50ml
💡DETAILS: [Dropper bottle: CBD Marula Oil, Secret Essential Oils] It is quickly absorbed and supports skin regeneration. Hydrates and revitalizes the skin. The secret essential extracts contained in the product help with emotional strain, stress and at the same time have a stimulating effect. The oil also contains omega fatty acids, which are the key to healthy skin, as well as vitamins D and E. It can be used as a tonic for hair nutrition, or in the bath as aromatherapy.
🔴MY REVIEW: CBD has recently become a new favorite in the beauty industry. Its excellent calming, soothing and anti-inflammatory effects can effectively improve skin problems. My skin is sensitive to redness, so I will use this CBD-containing Marula skin care oil before going to bed. Only two to three drops each time can calm the skin, reduce redness, and protect the skin. The barrier is strengthened. If you have sensitive skin like me, then MOIA ELIXIRS N°01 is definitely worth a try! MOIA ELIXIRS N°01 can reduce skin inflammation, soothe the skin and balance oil. Another key effect is that CBD is rich in fatty acids, which can fill the gaps between skin cells and increase the water retention of skin cells, thereby achieving a very good moisturizing effect. Good product worth recommending!
3. 5% CBD drops 10ml
4. 10% CBD drops 10ml
5. 15% CBD drops 10ml
💡[3-5] DETAILS: [Full Spectrum Elixirs] Activates the endocannabinoid system, thereby supporting the immune system and beneficially acting on the body's natural processes, helping the immune system to be in balance. According to studies, it has a demonstrable effect on anxiety or depression, positively stimulates the brain and more. MOIA ELIXIRS with CBD harmonize the natural processes in the body, have a positive effect on heart rate, cholesterol levels, skin condition, muscle and joint function.
🔴[3-5] MY REVIEW: CBD is very popular in Asia in recent years. The reason is that CBD, an ingredient, has many functions to help the body and skin recover. Aiming at reducing fine lines and wrinkles, it has a skin repair and balance effect, helps moisturize dry skin, relieves skin redness and evens skin tone. Don't be scared by the literal meaning of CBD. CBD extracted from natural ingredients, although extracted from cannabis plants, is absolutely free of drugs and can be used legally and safely. CBD also has powerful benefits in oral health products. Because of its non-drug and non-toxicity, CBD will not cause problems such as dependence, drug resistance or addiction, and eating edible products with different contents of CBD can achieve different physical and mental effects. For example, the 5% low content I tried can help calm the mood and increase concentration. A moderate content of 10% can relax the mood and have a significant effect on reducing stress and anxiety. The high content of 15% is very effective in improving the quality and state of sleep, entering a deep golden sleep, allowing the body and spirit to be truly rested and restored. The non-medicinal sedative effect of CBD can help the body and muscles to relieve pain and rest, and accelerate the recovery of muscle cells. The above three products have a clear oil body, a light and non-greasy texture. They are easy to mix with saliva and quickly absorbed when eaten directly, or can be easily mixed with drinks for drinking without affecting the taste. I have used these three products for more than a month, and the products help relax stress, mental tension and other states. Significantly improve mood quality and achieve a relaxed, happy feeling of myself. It relieves body and muscle pain, and also helps muscle tissue to recover. After use, it can help sleep easier to fall asleep. Definitely recommend these.
📌Disclaimer: The above review is purely personal opinion. Not everyone likes what I like. Please note that what may work for me, may not work for anyone else. Results may vary from person to person, so please take this into consideration if you decide to try those products.
🔎OFFICIAL WEBSITE - https://www.moiaelixirs.com
🔎FACEBOOK - https://www.facebook.com/moiaelixirs/
🔎IG - @moiaelixirs
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【藥事知多D】破解亞士匹靈削胃的秘密
〈點解亞士匹靈咁傷胃?〉
亞士匹靈(Aspirin)的第一印象總是離不開「削胃」。
對,亞士匹靈的其中一個聞名副作用便是「削胃」。因為亞士匹靈可能會削弱胃壁的自我保護機制,從而可能會刺激腸胃,導致腸胃不適,俗稱「削胃」。
不過除了亞士匹靈外,舉凡大部分的非類固醇消炎止痛藥(Non-steroidal Anti-inflammatory Drugs, NSAIDs)同樣都可能會影響胃壁的黏液分泌而「削胃」。
所以說到「削胃」,亞士匹靈只是其一,不是唯一。
平心而論,在芸芸眾多非類固醇消炎止痛藥裡,單是「削胃」這個副作用,亞士匹靈的相對風險還是較低[1],這就是說,在其他非類固醇消炎止痛藥前,亞士匹靈還可以說是「小巫見大巫」。
話雖如此,不過「低」風險不代表「零」風險,還是需要做好一些風險管理措施。所以不論是亞士匹靈還是其他非類固醇消炎止痛藥,一般建議餐後服用或者同時服用胃藥。
問題是,理論是一回事,現實卻是另一回事。
實際上,根據經驗,說到「削胃」,人們大多只會聯想到亞士匹靈,很少會聯想到其他非類固醇消炎止痛藥。
這方面,亞士匹靈的知名度就是遠遠較其他非類固醇消炎止痛藥來的大!
為什麼?
一般主要有以下四個原因:
第一,在化學上,亞士匹靈是一種弱酸,姑且撇開其他因素不說,自身的酸性便已經是一個潛在的誘因「削胃」。
第二,在藥理上,亞士匹靈還能夠直接作用於胃壁黏膜,導致胃酸出現反擴散(Back-diffusion)的現象,從胃腔(Gastric Lumen)回流到胃壁黏膜「削胃」。
第三,在用法上,現在亞士匹靈主要是一種抗血小板藥(Antiplatelet),適用於預防中風,俗稱「通血管」。所以一般建議長期服用,防患未然。
既然是長期服用,藥齡愈長,副作用自然一般便會愈大。
第四,要是亞士匹靈是用來「通血管」,不難想像這類用藥者的年紀一般會較大。
年紀愈大,副作用一般便會愈大。
所以真的要說的話,亞士匹靈還是存在一定的「削胃」風險。
那到底有沒有方法可以減少這種風險呢?
答案是有的。
唔……一般主要有以下三個對策:
第一,在調配上,搭配一些鹼鹽,例如碳酸鈣(Calcium Carbonate, CaCO3)、碳酸氫鈉(Sodium Bicarbonate, NaHCO3),主要有以下兩個目的:
其一,鹼鹽既能中和胃液,又能中和亞士匹靈與生俱來的酸性,總之結果只有一個,便是增加胃部的酸鹼值緩和「削胃」。
其二,鹼鹽可能會促進亞士匹靈進行離子化(Ionization),從而促進亞士匹靈在消化道內的吸收,固然可能會加快藥效[2],理論上,同時可能會縮短亞士匹靈逗留在消化道的時間,從而減少亞士匹靈對腸胃的局部影響。
第二,在調配上,搭配一些氨基酸例如Glycine、Lysine,一般宣稱這種組合能夠促進亞士匹靈的分散,從而促進亞士匹靈的吸收。
第三,在劑型上,採用腸溶片(Enteric-coated Tablets)「只溶於腸,不溶於胃」,希望讓亞士匹靈能夠繞過胃部直達小腸進行分解、吸收,減少對胃壁的刺激。
值得一提,跟前兩者不同,這方法並不是促進亞士匹靈的吸收,反而是減慢亞士匹靈的吸收緩和「削胃」。相較前兩者而言,藥效自然較慢,所以未必適合做一種即時止痛的止痛藥。
不過說到止痛藥,其實有很多選項,未必真的需要使用亞士匹靈。
何況現在亞士匹靈一般主要用來「通血管」。
所以問題一般不大。
(如欲了解更多用藥資訊,歡迎看看「小小藥罐子」網誌。)
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Reference:
1. Castellsague J, Pisa F, Rosolen V, Drigo D, Riera-Guardia N, Giangreco M, Clagnan E, Tosolini F, Zanier L, Barbone F, Perez-Gutthann S. Risk of upper gastrointestinal complications in a cohort of users of nimesulide and other nonsteroidal anti-inflammatory drugs. Pharmacoepidemiol Drug Saf. 2013 Apr;22(4):365-75.
2. Alan Nathan. Non-prescription Medicines. Pharmaceutical Press. 3rd ed. 2006:305-332.
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【藥事知多D】亞士匹靈抗性 = ?
有時劑量決定用途。
例如亞士匹靈(Aspirin)。
亞士匹靈一般有兩種技能,其一是消炎止痛藥,消炎止痛;其二是抗血小板藥,預防中風,俗稱「通血管」。
一般建議高劑量的亞士匹靈適用於消炎止痛;低劑量的亞士匹靈適用於預防中風。
其中「消炎止痛」的口服劑量是成人一天不宜服用超過4000mg (4g)的亞士匹靈。[1]
至於「通血管」的理想劑量暫時還是眾說紛紜,各國有各自的答案,其中一個參考答案是每天服用75至150mg的亞士匹靈。[2]
話雖如此,不過有時用藥者還是可能需要服用高劑量的亞士匹靈來預防中風。
這話怎麼解?
不說不知道,服用亞士匹靈原來可能會出現「亞士匹靈抗性(Aspirin Resistance)」這個問題。
在概念上,「亞士匹靈抗性」其實跟「耐受性(Drug Tolerance)」倒是有幾分異曲同工之妙的味道,簡單說,是指就算達到「通血管」的建議劑量,亞士匹靈還是不能抑制血小板凝聚,往往需要透過增加藥物的劑量,達到「通血管」的效果。[3]
各位看倌可能會問:
「噯!藥罐子,與其增加劑量,倒不如直接轉藥,不就行了嗎?」
對,如果命運能選擇……
遺憾的是,綜觀常用的抗血小板藥(Antiplatelet),裡面其實沒有太多選項,來來去去,不是這個,便是那個,一般只有三種:亞士匹靈、Clopidogrel、Dipyridamole。
其中相較Clopidogrel、Dipyridamole而言,亞士匹靈一般還是首選。
所以暫時姑且撇開價格、副作用這些因素不說,要是增加劑量便能夠解決問題,何樂而不為?
問題是,一個人無緣無故為什麼會出現亞士匹靈抗性?
唔……其中一個常見的原因是相互作用。
舉例說,服用亞士匹靈前,要是先服用布洛芬(Ibuprofen)這種非類固醇消炎止痛藥(Non-steroidal Anti-inflammatory Drugs, NSAIDs),便可能會跟亞士匹靈進行競爭,阻斷亞士匹靈跟環氧化酶(Cyclo-oxygenase)結合,從而抗衡亞士匹靈抑制血小板凝聚的功能,削弱「通血管」的效果。[4]
所以服用布洛芬前,有人建議服藥前至少兩小時便要服用亞士匹靈或者服藥後待到至少四小時後才能服用亞士匹靈,盡量避免出現亞士匹靈抗性的機會。
(如欲了解更多用藥資訊,歡迎看看「小小藥罐子」網誌。)
💊💊💊💊💊💊💊
BLOG➡️http://pegashadraymak.blogspot.com/
IG➡️https://www.instagram.com/pegashadraymak/
YT➡️https://www.youtube.com/channel/UCQOMojMd6q7XnESMWwldPhQ
📕📕📕📕📕📕📕
著作➡️藥事知多D、用藥知多D、藥房事件簿、家居用藥攻略(各大書店有售)
Reference:
1. British National Formulary. BMJ Group and RPS Publishing. 56th ed. 2008:228-229.
2. Charles Warlow. Aspirin Should Be First-Line Antiplatelet Therapy in the Secondary Prevention of Stroke. Stroke. 2002;33:2137-2138.
3. Eikelboom JW, Hankey GJ. Aspirin resistance: A new independent predictor of vascular events? J Am Coll Cardiol. 2003;41:966-968.
4. Catella-Lawson F, Reilly MP, Kapoor SC, et al. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. N Engl J Med. 2001;345:1809-1817.
anti inflammatory drug 在 Anti-inflammatory Drugs, Pharmacology, Animation - YouTube 的推薦與評價
Anti - inflammatory drugs : "Aspirin", naproxen, ibuprofen, diclofenac, celecoxib and "Tylenol" · Anti - inflammatory drugs (NSAIDs and steroids). ... <看更多>