藥物，化妝品都有可能有 Parabens
而這會生出 ROS ，影響精子質量，破壞 DNA
#Parabens and HIS fertility -- Antimicrobial #preservatives are actually #preservatives: #ROS increase may harm human sperm
We already know that they have weak oestrogenic and antiandrogenic activities, the antimicrobial preservative agents from many commercial products including cosmetics and pharmaceuticals, now research indicates that a mixture of common parabens is "capable of stimulating the generation of mitochondrial and cytosolic reactive oxygen species (ROS), inhibiting sperm motility and viability in a dose‐dependent manner".
"Taken together, [our] data underline the potential cytotoxic and genotoxic impact of such compounds in a clinical setting," the authors highlight.
suppversity.com | Samarasinghe, S. V., Krishnan, K. , Naidu, R. , Megharaj, M. , Miller, K. , Fraser, B. and Aitken, R. J. (2018), Parabens generate reactive oxygen species in human spermatozoa. Andrology.doi.org/10.1111/andr.12499
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