TSC Protein Complex, mTOR Complex 1, and Downstream Effects. The tuberous sclerosis complex (TSC) proteins, which include TSC1, TSC2, and TBC1D7, are negatively regulated by phosphorylation (+P) by AKT, ERK, and RSK, which are all core kinases that are activated during growth signaling. This complex is activated under hypoxia and on phosphorylation by AMPK in response to energy stress and functions as a GTPase-activating protein to negatively regulate RHEB, a Ras family member GTPase. RHEB-GTP activates mechanistic target of rapamycin (mTOR) complex 1 (mTORC1), which is also regulated by intracellular amino acid levels and has multiple direct kinase targets and even more secondary targets of phosphorylation. In some cases, the mechanism of regulation is not completely understood (as indicated by a dashed line). In aggregate, these transcription factors, translation factors, and enzymes lead to biosynthesis of ribosomes and other components that are needed for efficient translation, including ATP and amino acids, as well as lipid precursors, NADPH, nucleotides, RNA, and DNA, to enable an increase in cell size and growth. Arrows indicate stimulatory events, which at times are mediated by phosphorylation; blocked lines indicate inhibitory effects. Biallelic (complete) loss of TSC1 or TSC2 leads to the loss of negative regulatory effects of the TSC protein complex and constitutive activation of mTORC1. CAD denotes carbamoyl-phosphate synthetase 2, aspartate transcarbamoylase, dihydroorotase; EIF4E eukaryotic translation initiation factor 4E; 4EBP1 eukaryotic translation initiation factor 4E binding protein 1; G6PD glucose-6-phosphate dehydrogenase; HIF1A hypoxia-inducible factor 1α; PPP pentose phosphate pathway; SREBP1 sterol regulatory element-binding protein 1; and S6K1/2 ribosomal protein S6 kinase 1 and 2.
同時也有1部Youtube影片,追蹤數超過1萬的網紅kormaruR,也在其Youtube影片中提到,ファイナルファンタジーXIII Final Fantasy XIII Turn on Annotation! First Aspect: Game Over Screen Watch and see for yourself. Aspect 2: Additional tips...
「initiation of translation」的推薦目錄:
initiation of translation 在 kormaruR Youtube 的最佳貼文
ファイナルファンタジーXIII
Final Fantasy XIII
Turn on Annotation!
First Aspect: Game Over Screen
Watch and see for yourself.
Aspect 2: Additional tips for the impatient one, ME! ;D
found this one when I finally get my hands back on Snow.
Little background before the finding -
Quick ATB command initiation: Press △ after you queue up the ATB commands. Like explained in MasterLL's first advanced battle technique video 1.
http://www.youtube.com/watch?v=Zsi95tRRS4Y
Ok. So during my battle with Snow I got impatient to wait for the slow charging turn of ATB gauge to become full (before this chap. I use to have 3 ATB gauge slot but now its 4!), I just did a quick initiation.
Upon doing that, I just optima change and to my surprise, I get a full ATB gauge too O.o;
So yea, ATB gauge gets fill full every other optima change. Which totally encourage you to optima change often just to take advance of faster ATB refills ;D
Tips: Use quick command initiation wisely to your advantage. Do a quick command initiation to clear off a dieing enemy so that s/he does not get another turn to hit your party.
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Requested minor libra translation???
http://img192.imageshack.us/img192/470/192010123252pm.png
initiation of translation 在 The mechanism of eukaryotic translation initiation and ... 的相關結果
Translation initiation is the process of assembly of elongation-competent 80S ribosomes, in which the initiation codon is base-paired with the anticodon ... ... <看更多>
initiation of translation 在 Molecular mechanisms of translation initiation in eukaryotes 的相關結果
Translation initiation is a complex process in which initiator tRNA, 40S, and 60S ribosomal subunits are assembled by eukaryotic initiation ... ... <看更多>
initiation of translation 在 Stages of translation (article) | Khan Academy 的相關結果
Initiation ("beginning"): in this stage, the ribosome gets together with the mRNA and the first tRNA so translation can begin. · Elongation ("middle"): in this ... ... <看更多>