關於 pirfenidone ，我們在網路上蒐集到這些相關的討論、資訊與評價

#11. Pirfenidone ≥97% (HPLC) | 53179-13-8 - Sigma-Aldrich

Pirfenidone ≥97% (HPLC); CAS Number: 53179-13-8; Synonyms: 5-Methyl-1-phenyl-2-(1H)-pyridone; find Sigma-Aldrich-P2116 MSDS, related peer-reviewed papers, ...

#12. 特發性肺纖維化的新進展(下)

在IPF 患者中其他致病和死亡的原. 因還包括冠狀動脈疾病、肺栓塞及肺癌。 藥物治療. 2014年nintedanib 和pirfenidone 兩種藥物的臨床最新試驗結果，同時發表在新英格. 蘭 ...

#13. Low-Dose of Intrapulmonary Pirfenidone Improves Human ...

Idiopathic pulmonary fibrosis is a chronic, progressive, and lethal lung disease of unknown etiology. Antifibrotic drugs, including pirfenidone, ...

#14. Esbriet (pirfenidone) dosing, indications, interactions, adverse ...

USES: Pirfenidone is used to treat a certain lung disease called idiopathic pulmonary fibrosis (IPF). This disease causes the lungs to get scarred and become ...

#15. Pirfenidone in heart failure with preserved ejection fraction

Pirfenidone is an oral, small-molecule, antifibrotic agent without hemodynamic effect, that is approved for patients with idiopathic pulmonary ...

#16. Pirfenidone - an overview | ScienceDirect Topics

Pirfenidone is an orally active pyridone derivative that has been approved in Europe as an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis ...

#17. 公告修訂含pirfenidone成分藥品（如Pirespa）之藥品給付規定

公告修訂含pirfenidone成分藥品（如Pirespa）之藥品給付規定. 分類：健保署日期：2020-07-27. 衛生福利部中央健康保險署公告. 發布日期109.07.20.

#18. esbriet-epar-public-assessment-report_en.pdf - European ...

Pirfenidone was designated as an orphan medicinal product in the following indication: the treatment of idiopathic pulmonary fibrosis (IPF).

#19. Pirfenidone: MedlinePlus Drug Information

Pirfenidone is used for the treatment of idiopathic pulmonary fibrosis (scarring of the lungs with an unknown cause). Pirfenidone is in a class of ...

#20. Pirfenidone: Uses, Interactions, Mechanism of Action - DrugBank

Pirfenidone is an orally active small molecule drug that may inhibit collagen synthesis, down regulate production of multiple cytokines and block fibroblast ...

#21. PIRFENIDONE | Drug | BNF content published by NICE

The exact mechanism of action of pirfenidone is not yet understood, but it is believed to slow down the progression of idiopathic pulmonary fibrosis by ...

#22. Esbriet (pirfenidone) - Roche

Esbriet (pirfenidone). esbriet-740. Esbriet is an oral anti-fibrotic medicine approved for the treatment of Idiopathic Pulmonary Fibrosis (IPF), ...

#23. Safety and Efficacy of Pirfenidone in Patients With Idiopathic ...

Idiopathic Pulmonary Fibrosis, Drug: Pirfenidone Drug: Placebo, Phase 3 ... to receive pirfenidone 2403 milligrams or placebo equivalent administered in ...

#24. Limited Coverage Drugs – Pirfenidone - Government of British ...

Special Authority Criteria. Approval Period. Initial: For the treatment of mild to moderate idiopathic pulmonary fibrosis (IPF) in adult patients:.

#25. Esbriet 267 mg Film-coated Tablets - eMC

Pirfenidone attenuates fibroblast proliferation, production of fibrosis-associated proteins and cytokines, and the increased biosynthesis and accumulation of ...

#26. pirfenidone oral: Uses, Side Effects, Interactions, Pictures ...

Pirfenidone is used to treat a certain lung disease called idiopathic pulmonary fibrosis (IPF). This disease causes the lungs to get scarred and become ...

#27. Pirfenidone Uses, Side Effects & Warnings - Drugs.com

Pirfenidone is used to treat a lung disease called idiopathic pulmonary fibrosis (IPF). IPF causes scar tissue to form deep within your ...

#28. Pirfenidone (CAS 53179-13-8) - R&D Systems

Pirfenidone is a antifibrotic agent, effective in models of pulmonary and lung fibrosis. Inhibits collagen production and fibroblast proliferation.

#29. FAQ: Pirfenidone | Patient Education | UCSF Health

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#30. Pirfenidone (AMR69) | TGF-beta/Smad Inhibitor

Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and ...

#31. Pirfenidone for Idiopathic Pulmonary Fibrosis: A Systematic ...

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor prognosis. In the last decades pirfenidone an anti-inflammatory and ...

#32. Effect of pirfenidone on lung function decline and survival: 5-yr ...

Pirfenidone, an antifibrotic drug, slows-down the disease progression in idiopathic pulmonary fibrosis (IPF) over 12 months, however limited ...

#33. Pirfenidone (Oral Route) Side Effects - Mayo Clinic

Pirfenidone is used to treat idiopathic pulmonary fibrosis. This medicine is available only with your doctor's prescription.

#34. PIRE - 藥品資料

6.2.7.Nintedanib(如Ofev)、 pirfenidone（如Pirespa）： (106/3/1、106/7/1、108/12/1、 109/9/1、110/6/1） 1.特發性肺纖維化： (1)需檢附肺部HRCT (High resolution ...

#35. Pirfenidone for Idiopathic Pulmonary Fibrosis - ATS Journals

The antifibrotic agent pirfenidone was recently approved for treatment of IPF. Pirfenidone was evaluated in two multinational phase 3 trials (CAPACITY ...

#36. 健保資訊

Nintedanib(如Ofev)、pirfenidone（如Pirespa）：(106/3/1、106/7/1） 1.需檢附肺部HRCT (High resolution computed tomography)影像檢查。

#37. Pirfenidone in Heart Failure With Preserved Ejection Fraction

Contribution To Literature: The PIROUETTE trial showed that pirfenidone was beneficial at reducing myocardial fibrosis among patients with HFpEF ...

#38. Esbriet® (pirfenidone) - Information for Patients - Genentech

Esbriet is a prescription medicine used to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF). It is not known if Esbriet is safe and ...

#39. Treatment of idiopathic pulmonary fibrosis - UpToDate

Pirfenidone. US Food and Drug Administration (FDA) approved product information. US National Library of Medicine. http://dailymed.nlm.nih.gov/dailymed/ ...

#40. integrated analysis of cumulative data from 5 clinical trials

Background Pirfenidone is an oral antifibrotic agent that has been shown to reduce the decline in lung function in patients with idiopathic pulmonary fibrosis ( ...

#41. Pirfenidone (S-7701) | ≥99%(HPLC) - Selleck Chemicals

Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fi.

#42. 特發性肺纖維化的藥物處置- Pirfenidone、Nintedanib - 新光醫院

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#43. Pirfenidone (AMR 69, CAS Number: 53179-13-8) - Cayman ...

Formulations containing pirfenidone have been used in the treatment of idiopathic pulmonary fibrosis. WARNING This product is not for human or veterinary use.

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Esbriet ® (pirfenidone) is a prescription medicine used to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).

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View and buy high purity Pirfenidone from Tocris Bioscience. Antifibrotic agent; regulates cytokine levels in vivo. Cited in 1 publication.

#46. Effects of Pirfenidone on Proliferation, Migration, and Collagen ...

After treatment of HTFs with pirfenidone, cell proliferation was measured by MTT assay. Cell migration was investigated by scratch assay. Contractility was ...

#47. Pirfenidone inhibits proliferation, arrests the cell cycle, and ...

Pirfenidone inhibits proliferation, arrests the cell cycle, and downregulates heat shock protein‑47 and collagen type I in rat hepatic stellate ...

#48. Pirfenidone: significant treatment effects in idiopathic ...

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#49. Treatment-idiopathic pulmonary fibrosis. - NHS

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#50. A Novel Pharmacological Agent That Inhibits Leiomyoma Cell ...

Pirfenidone (Marnac, Inc.) is an antifibrotic agent that is being tested for use in patients with pulmonary fibrosis. Because leiomyomas are characterized also ...

#51. Esbriet (pirfenidone) dose, indications, adverse ... - PDR.net

If a strong CYP1A2 inhibitor is the only drug of choice available, reduce the pirfenidone dosage to 267 mg 3 times daily. If concurrent treatment with a ...

#52. Enhancing the Pharmaceutical Properties of Pirfenidone by ...

Pirfenidone is an important drug molecule used in the treatment of idiopathic lung fibrosis. Although approved by the USFDA in 2014, ...

#53. Role and New Insights of Pirfenidone in Fibrotic Diseases

Pirfenidone (PFD) is a non-peptide synthetic molecule issued as a broad-spectrum anti-fibrotic drug with the ability to decrease TGF-β1, TNF-α, PDGF and ...

#54. Pirfenidone in Idiopathic Pulmonary Fibrosis - Karger Publishers

Background: Pirfenidone is a novel antifibrotic drug for the treatment of mild-to-moderate idiopathic pulmonary fibrosis (IPF).

#55. Pirfenidone (Esbriet): risk of serious liver injury - GOV.UK

Measure alanine aminotransferase (ALT), aspartate aminotransferase (AST), and bilirubin levels before starting pirfenidone treatment, monthly ...

#56. Pirfenidone and Nintedanib: Novel Agents in the Treatment of ...

Pirfenidone is a small molecule inhibitor of several pathways implicated in fibrosis, including transforming growth factor beta (TGFβ), ...

#57. Esbriet (Pirfenidone Capsules): Uses, Dosage, Side Effects ...

Esbriet (Pirfenidone Capsules) may treat, side effects, dosage, drug interactions, warnings, patient labeling, reviews, and related medications including ...

#58. 藥物成分劑型編號Pirfenidone 口服藥

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#59. Pirfenidone Inhibits Cell Proliferation and Collagen I ... - MDPI

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#60. pirfenidone | Michigan Medicine

Pirfenidone is used to treat a lung disease called idiopathic pulmonary fibrosis (IPF). IPF causes scar tissue to form deep within your lungs.

#61. Draft Guidance on Pirfenidone Active Ingredient - Accessdata ...

To discuss an alternative approach, contact the Office of Generic Drugs. Active Ingredient: Pirfenidone. Dosage Form; Route: Tablet; oral. Recommended Studies: ...

#62. Pirfenidone, orally active anti-inflammatory antifibrotic agent ...

MW 185.23, Purity > 99%. Orally active anti-inflammatory, antifibrotic and antiproliferative agent. Blood-brain barrier permeable.

#63. Esbriet® (pirfenidone) Information for Healthcare Professionals

Learn about Esbriet® (pirfenidone) as a possible treatment option for IPF, a progressive and irreversible fibrotic interstitial lung disease.

#64. Pirfenidone for the treatment of idiopathic pulmonary fibrosis

In 2014 however, the emergence of two novel anti-fibrotic agents, Pirfenidone and Nintedanib revolutionized the management of this condition.

#65. A Review of Pirfenidone as an Anti-Fibrotic in Idiopathic ...

PFD: pirfenidone; IPF: idiopathic pulmonary fibrosis: FVC: forced vital capacity; TGF-β1: transforming growth factor-beta one; CTHRC1: collagen ...

#66. Pirfenidone and Nintedanib: Tips for Treating Patients with ...

#67. Pirfenidone Initiates a New Era in the Treatment of Idiopathic ...

Randomized clinical trials have demonstrated that treatment with pirfenidone in patients with IPF reduces decline in lung function as measured by forced vital ...

#68. versión On-line ISSN 0717-9707 - SciELO Chile

Pirfenidone is a new drug approved for the treatment of rare and generally incurable idiopathic pulmonary fibrosis (IPF). Patients with IPF suffer from ...

#69. Pirfenidone: A Unique Antifibrotic and Anti-Inflammatory Agent

Pirfenidone (1) is a bioactive small molecule, and was first reported as an anti-inflammatory agent in the 1970s. 1) Recently, Oku et al. have reported its ...

#70. Pirfenidone Gets Breakthrough Therapy Status for ...

The FDA has granted Breakthrough Therapy designation to pirfenidone (Esbriet®; Genentech) for adults with fibrosing interstitial lung ...

#71. Online Pirfenex 250Mg-Pirfenidone Tablets - IndiaMART

Pirfenex medicine contains generic Pirfenidone . Pirfenidone are available in form of Tablet. Each Coated Tablet contains 200Mg Pirfenidone. One Pack of ...

#72. Pirfenidone Slows Long-Term Progression of Idiopathic ...

Fewer than 25% of patients with idiopathic pulmonary fibrosis who were treated with the antifibrotic drug pirfenidone showed signs of ...

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#74. Pirfenidone targets. Different targets in vivo and in vitro for PFD...

Pirfenidone (PFD) is a non-peptide synthetic molecule issued as a broad-spectrum anti-fibrotic drug with the ability to decrease TGF-beta 1, TNF-alpha, ...

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#76. Pulmonary Fibrosis: New Insights for the Healthcare ...

In some embodiments, the patient is a patient who was a smoker immediately prior to starting administration of pirfenidone. In some embodiments, the patient ...

#77. Mirfendo 200 MG ( Pirfenidone) | MBA Pharmaceuticals Pvt Ltd

Medicine composition: Pirfenidone. Mirfendo 200mg Tablet is an antifibrotic agent. It is used to treat mild cases of a lung disease called idiopathic ...

#78. PIRFENEX 400mg Tablet 15's - Buy Medicines online at Best ...

PIRFENEX 400MG contain pirfenidone which belongs to a group of medicine called pyridones. It is used to treat mild to moderate Idiopathic Pulmonary Fibrosis ...

#79. Esbriet 267 mg 270 Capsules - Nahdi

Pirfenidone 267 mg Hard Capsules What Pirfenidone is used for : Pirfenidone is used for the treatment of mild to.

#80. Pirfenidone found safe, efficacious in idiopathic pulmonary ...

Pirfenidone has been found safe, and efficacious in idiopathic pulmonary fibrosis (IPF) in a real-world cohort study.

#81. 美国APExBIO中文官网- Pirfenidone

Pirfenidone 是一种口服抗纤维化剂，具有广谱抗纤维化和抗炎作用。Pirfenidone用于治疗某些纤维化疾病，在特发性肺纤维化患者中，Pirfenidone目前已进入处于临床试验中 ...

#82. Pirfenidone 200mg Tablet Pirfenex - M Care Exports

Pirfenidone 200 mg Tablet, which is used in the treatment of idiopathic pulmonary fibrosis, have been shown to be effective in this condition.

#83. Fibrodone Tablet - Uses, Dosage, Side Effects, Price ... - Practo

ContainsPirfenidone. Description. Fibrodone Tablet is used to treat idiopathic pulmonary fibrosis, a progressive lung disease that causes ...

#84. Interstitial Lung Diseases: European Respiratory Monograph

42, 16, and 36 patients discontinued treatment prematurely with pirfenidone 1,800 mg?day-1, pirfenidone 1,200mg?day-1 and placebo, respectively.

#85. Pirfenidone (新型藥物治療原發性肺部纖維化) - 藥師家

Pirfenidone (新型藥物治療原發性肺部纖維化). 在美國及歐洲每年大約有30000名原發性肺部纖維化(IPE) 新案例，估計目前約有200000萬病患，未獲有效藥物控制。

#86. Pirfenidone (AMR69) - Pirespa; Pirfenex; Deskar, Esbriet

Pirfenidone (formerly AMR69; S7701, AMR-69; S-7701; trade name: Pirespa; Pirfenex; Deskar, Esbriet) is a potent inhibitor for TGF-β production and TGF-β ...

#87. Pirfenex (Pirfenidone) 200mg | Pharmasepa

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MarketQuest.biz has published Global Pirfenidone Market 2021 by Manufacturers, Regions, Type and Application, Forecast to 2027 that provides ...

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Pirfenidone की खुराक और इस्तेमाल करने का तरीका - Pirfenidone Dosage & How to Take in Hindi · बीमारी: इडियोपैथिक ...

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#91. Management of Idiopathic Pulmonary Fibrosis - Pharmacy ...

In 2014, the FDA approved 2 oral antifibrotic therapies for IPF: nintedanib (Ofev, Boehringer Ingelheim) and pirfenidone (Esbriet, ...

#92. Pirfetab(Pirfenidone) For The... - Alijana Medical Store

#93. 肺纤维化治疗网| 吡非尼酮（Pirfenidone）艾思瑞（Etuary）

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#94. Pulmonary Emergencies: ERS Monograph - 第 124 頁 - Google 圖書結果

Antifibrotic drugs in AE-IPF Since the adjusted guideline on diagnosis and treatment of IPF [80], the antifibrotic drugs pirfenidone and nintedanib have ...

#95. Clinical Handbook of Interstitial Lung Disease - Google 圖書結果

(EMA) approved pirfenidone in 2011, while in the United States, the Food and Drug Administration (FDA) specifically requested a further multinational, ...

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