EGFR exon 19 deletions were identified in parental and gefitinib-resistant cells, but no secondary T790M mutation of EGFR was detected in either cell line.
The expression of EGFR exon 19 deletion and its clinical significance in the squamous cell lung cancer,lung adenocarcinoma · 【分類號】R734.2 · 【網絡出版時間】 ...
The mutations of epidermal growth factor receptor (EGFR) on exon 19 deletion and exon 21 point mutation are respond well to the first and second generation ...
晚期肺癌血清游离DNA中EGFR外显子19的基因突变研究(An exon 19 mutation of EGFR ... The mutations in exon 19 were all in frame deletion of the codon 746 to 753, ...
#43.
双倍剂量埃克替尼治疗EGFR 基因敏感突变肺腺癌柔脑膜转移 ...
The CSF had an exon 19 deletion mutation in the EGFR gene, and no sensitive mutations were found in blood sample. Oral icotinib hydrochloride 250 mg/time (3 ...
Analysis on the correlation of Fn14 and JAK／STAT signal pathway in non small cell lung cancer with EGFR exon 19 deletion. YANG Sanhu， YANG Feng， ZHANG ...
Mechanism and Management of Primary Resistance to Targeted Therapy in NSCLC Patients Harboring EGFR Sensitive Mutations. LIANG Wenhua1*，LI Caichen1，LIANG ...
#70.
肺癌EGFR基因19缺失突變有更好生存期，是什麼起了作用？
肺癌 中的非小細胞肺腺癌是靶向治療最為成熟的肺癌亞型，有很高的頻率是EGFR ... Better Survival of Patients with Exon 19 Deletions Compared with ...
#71.
晚期非小细胞肺癌抗血管生成药物的联合治疗模式
抗血管生成药物在晚期非小细胞肺癌中应用广泛，不仅能通过抑制肿瘤新生血管来抑制肿瘤 ... especially those with EGFR exon 19 deletion mutations, ...
#72.
40岁以下非小细胞肺癌中EGFR突变状态和PD-L1的表达
40岁以下非小细胞肺癌中EGFR突变状态和PD-L1的表达 ... In youth group, the 19del and 20ins were more frequent, but the exon 21 L858R point mutation proportion ...
#73.
中国科学家系统评价非小细胞肺癌一线治疗的疗效 - 论文
两种最常见的EGFR突变类型的亚组分析表明，在外显子19缺失的患者中，奥希替 ... progression free survival in patients with the exon 19 deletion, ...
#74.
中国肺癌杂志www.lungca.org - Sci-Hub
（P<0.05）；实体型肺腺癌在ALK阳性组中比例明显增高，而腺泡型与贴壁型比例明显 ... adenocarcinoma with EGFR exon 19 deletion (×400); C: Low expression (1+) in ...
#75.
人非小细胞肺癌P16基因突变研究 - 中国普通外科杂志
结果45例肺癌样品中共检出19例p16基因缺失，总的缺失率 ... Methods Deletion and mutation at p16 gene exons 1 2 were determined in 45 human non small ...
focused on exon 19 deletions and L858R mutation. The result showed no signal in 3 out of the 70 patients, which may be due to insufficient amount of DNA.
#89.
Prognostic value of EGFR 19‑del and 21‑L858R mutations in ...
... patients with non‑small cell lung cancer (NSCLC) harboring exon 19 deletion (19‑del) and an exon point mutation (21‑L858R) in EGFR.
exon 19 deletion肺癌 在 蔡俊明教授肺癌說明白- 只要談到EGFR（上皮生長因子受體 ... 的推薦與評價
人體一共有23對染色體，而EGFR基因就位在第七號染色體的短臂，其中最常見的突變類型有兩種，一是發生在19位點的缺損exon 19 deletion (Del 19) ，一是 ... ... <看更多>