MST2 kinase localises at the nucleoli and targets phosphorylation of H2BS14p in an ATM-dependent manner. Ablation of MST2 kinase, or upstream ... ... <看更多>
「mst2 gene」的推薦目錄：
mst2 gene 在 Mst1 and Mst2 kinases: regulations and diseases 的相關結果
The serine/threonine protein kinases Mst1 and Mst2, mammalian homologs of the Hippo kinase from Drosophila, play the central roles in the Hippo ... ... <看更多>
mst2 gene 在 STK3 - Wikipedia 的相關結果
Serine/threonine-protein kinase 3 is an enzyme that in humans is encoded by the STK3 gene. ... Aliases · STK3, KRS1, MST2, serine/threonine kinase 3. ... <看更多>
mst2 gene 在 SERINE/THREONINE PROTEIN KINASE 3; STK3 - OMIM 的相關結果
MAMMALIAN STERILE 20-LIKE 2; MST2 ... HGNC Approved Gene Symbol: STK3 ... MST2 was identified as a kinase that is activated by the proapoptotic agents ... ... <看更多>
mst2 gene 在 STK3 - Serine/threonine-protein kinase 3 | UniProtKB - UniProt 的相關結果
The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and ... ... <看更多>
mst2 gene 在 Molecular and functional characterization of MST2 in grass ... 的相關結果
In this study, we cloned the MST2 gene of Ctenopharyngodon idella (CiMST2) and analyzed its tissue distribution. CiMST2 was present in most of the studied ... ... <看更多>
mst2 gene 在 STK3 (serine/threonine kinase 3) 的相關結果
Mst2 and Lats kinases regulate apoptotic function of Yes kinase-associated protein (YAP). 155. 17889669, 2007, RASSF1A elicits apoptosis through ... ... <看更多>
mst2 gene 在 PomBase - protein coding gene - histone acetyltransferase Mst2 的相關結果
PMID:16199868 - Schizosaccharomyces pombe mst2+ encodes a MYST family histone acetyltransferase that negatively regulates telomere silencing. Gómez EB et al. ... <看更多>
mst2 gene 在 Human MST2, GST Tag Recombinant Protein (PV4806) 的相關結果
Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell ... ... <看更多>
mst2 gene 在 Functional Role of Mst1/Mst2 in Embryonic Stem Cell ... - PLOS 的相關結果
Next, we compared the expression of some later endoderm tissue markers in Mst-/- EBs and wild type EBs. Although the expression of some genes is disturbed due ... ... <看更多>
mst2 gene 在 The Histone Acetyltransferase Mst2 Protects Active Chromatin ... 的相關結果
Thereby, Mst2 binds to all tran- scriptionally active regions genome-wide. Besides acetylating histone H3K14, Mst2 also acetylates. Brl1, a ... ... <看更多>
mst2 gene 在 MST2/STK3 Gene Sequence, Family, Fuction and Expression ... 的相關結果
elegans, and frog. 199 organisms have orthologs with human gene STK3. All MST2/STK3 genes ... ... <看更多>
mst2 gene 在 STK3 - serine/threonine kinase 3 - WikiGenes 的相關結果
Synonyms: KRS1, MST-2, MST2, Mammalian STE20-like protein kinase 2, STE20-like ... genes to generate the expression profiles of the CCSST cell lines GG-62, ... ... <看更多>
mst2 gene 在 serine/threonine kinase 3 (MST2) - DiscoverX 的相關結果
serine/threonine kinase 3 (MST2). Target Class: Kinase; Family: STE; Official Symbol: STK3; Entrez Gene ID: 6788; Species: Human; Accession Number ... ... <看更多>
mst2 gene 在 MST2 (human) - PhosphoSitePlus 的相關結果
MST2 Stress-activated, pro-apoptotic kinase which, ... nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. ... <看更多>
mst2 gene 在 MST2(STK3) 的相關結果
SYMBOL | GENE NAME, STK3 | serine/threonine kinase 3. ALIAS, STK3,KRS1,MST2, LOCUS, 8q22.2. CLASS, Serine/Threonine Kinase, GROUP, STE. FAMILY, STE20. ... <看更多>
mst2 gene 在 serine/threonine kinase 3 | MST subfamily 的相關結果
Gene and Protein Information Click here for help ... Description: Crystal structure of MST2 in complex with XMU-MP-1. PDB Id: 5DH3. Ligand: XMU-MP-1. ... <看更多>
mst2 gene 在 MST2/STK3 Research Products - Novus Biologicals 的相關結果
Discover related pathways, diseases and genes to MST2/STK3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool. ... <看更多>
mst2 gene 在 STK3/MST-2 protein (STJ505784) - St John's Laboratory Ltd 的相關結果
STK3/MST-2-protein if for use in research applications. ... <看更多>
mst2 gene 在 Mst1 and Mst2 protein kinases restrain intestinal stem ... - PNAS 的相關結果
In the colon cancer cell lines SW480 and HCT116, which exhibit moderate Yap1 overabundance, depletion of Yap1 by shRNA-induced silencing of gene ... ... <看更多>
mst2 gene 在 KEGG ORTHOLOGY: K04412 的相關結果
Protein kinases [BR:ko01001] Serine/threonine kinases: STE group. STE20 family. K04412 STK3, MST2; serine/threonine kinase 3. BRITE hierarchy. Genes ... ... <看更多>
mst2 gene 在 017635 - mst1[fl] mst2[fl] Strain Details - The Jackson Laboratory 的相關結果
017635 STOCK Stk4 tm1.1Rjo Stk3 tm1.1Rjo /J These double floxed mutant mice possess loxP sites flanking exons 4-5 of the Stk4 gene and exons 5-6 of the Stk3 ... ... <看更多>
mst2 gene 在 Gene MST2 (Mouse) - Kinase.com 的相關結果
MST2. Species: Mouse. Alias: Stk3, MST2. External Links: MGI , Entrez Gene , Refseq cDNA , Refseq Protein , Phosphosite , iHOP. Annotation: ... ... <看更多>
mst2 gene 在 STK3 - Signalchem 的相關結果
STK3, also known as MST2, encodes a protein of 491-amino acid which contains an N-terminal catalytic domain characteristic of ... Gene 167: 303-306, 1995. ... <看更多>
mst2 gene 在 4L0N: Crystal structure of STK3 (MST2) SARAH domain 的相關結果
Crystal structure of STK3 (MST2) SARAH domain. ... 51, Homo sapiens, Mutation(s): 0. Gene Names: KRS1, MST2, STK3 EC: 2.7.11.1 ... ... <看更多>
mst2 gene 在 Mst2 histone acetyltransferase complex | SGD 的相關結果
Gene Ontology Term: Mst2 histone acetyltransferase complex. GO ID: GO:0036410; Aspect: Cellular Component; Description: A protein complex that can catalyze the ... ... <看更多>
mst2 gene 在 The Mammalian Ste20-like Kinase 2 (Mst2) Modulates Stress ... 的相關結果
Results: Genetic ablation of Mst2 reduces pathological cardiac hypertrophic ... association between a polymorphism in the human MST2 gene. ... <看更多>
mst2 gene 在 STK3/MST2 Rabbit mAb-Monoclonal Antibodies - ABclonal 的相關結果
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. ... <看更多>
mst2 gene 在 Rabbit anti-MST2/STK3 Antibody - Fortis Life Sciences 的相關結果
In response to apoptotic signals, MST2/STK3 is cleaved by caspase-3 and mediates apoptosis. Gene ID: 6788. Gene Symbol: STK3. Gene Name: ... ... <看更多>
mst2 gene 在 Mst2 Controls Bone Homeostasis by Regulating Osteoclast ... 的相關結果
ABSTRACT Mammalian sterile 20-like kinase 2 (Mst2) plays a central role in the Hippo ... Genetic ablation of Mst2 induces bone loss in mice. ... <看更多>
mst2 gene 在 MST1/MST2 Protein Kinases: Regulation and Physiologic Roles 的相關結果
The MST1 and MST2 protein kinases comprise the GCK-II subfamily of ... MST1/Hippo promoter gene methylation predicts poor survival in ... ... <看更多>
mst2 gene 在 Mst2 elisa kit - MyBioSource 的相關結果
Gene Names: STK3; KRS1; MST2. Other Names: Human Serine/threonine-protein kinase 3 (STK3) ELISA kit; FLJ90748; serine/threonine kinase 3; serine/threonine ... ... <看更多>
mst2 gene 在 12)(q22;p13) in acute myeloid leukemia | SpringerLink 的相關結果
Identification of a fusion gene composed of a Hippo pathway gene MST2 and a common translocation partner ETV6 in a recurrent translocation t(8; ... ... <看更多>
mst2 gene 在 MST2/STK3 Products - Bio-Techne 的相關結果
View 3 MST2/STK3 products. Bio-Techne offers high-quality reagents, instruments, custom manufacturing and testing services. ... <看更多>
mst2 gene 在 stk3 Summary - Xenbase 的相關結果
Gene Symbol: stk3. Gene Name: serine/threonine kinase 3. Synonyms: mst2 , xstk3 ( Nomenclature history ). Gene Function: STE20-like serine/threonine kinase ... ... <看更多>
mst2 gene 在 Abstract 11521: The Mammalian Ste20-like Kinase 2 (Mst2), a ... 的相關結果
Mice with genetic ablation of Mst2 gene (Mst2 -/- ) exhibited a significant reduction of hypertrophy in response to transverse aortic ... ... <看更多>
mst2 gene 在 MST2 - TAIR 的相關結果
MST2. Name Type (?) symbol. Gene Model Type (?) protein_coding. Description, Mercaptopyruvate sulfurtransferase. Chromosome, 1. Sequence (?) ... ... <看更多>
mst2 gene 在 Gene Sets Net Correlations Analysis (GSNCA): a multivariate ... 的相關結果
We show that genes in the center of MST2 have large weights, and we demonstrate that hub genes—genes with the largest weight in the pathways—correspond in real ... ... <看更多>
mst2 gene 在 pJ3M-Mst2 (Plasmid #12205) - Addgene 的相關結果
pJ3M-Mst2 (Plasmid #12205) · Ordering · Backbone · Growth in Bacteria · Gene/Insert · Cloning Information · Resource Information · Terms and Licenses · Depositor ... ... <看更多>
mst2 gene 在 Invitrogen STK3 (MST2) Recombinant Human Protein 的相關結果
STK3 (MST2) is a STE kinase family member that acts upstream of the MAP kinase signaling pathways, and is known to be activated by the proapoptotic stimuli. ... <看更多>
mst2 gene 在 Analysis of Liver Tumor-Prone Mouse Models of the Hippo ... 的相關結果
The tumor suppressor gene RASSF1A is epigenetically silenced in most human cancers. As a binding partner of the kinases MST1 and MST2, the mammalian ... ... <看更多>
mst2 gene 在 Human/Mouse/Rat MST2/STK3 Antibody - R&D Systems 的相關結果
Human MST2 is 99% and 96% aa identical to canine and mouse MST2, respectively. Entrez Gene IDs. 6788 (Human); 56274 (Mouse). Alternate Names. EC 2.7.11 ... ... <看更多>
mst2 gene 在 Genetic variants in Mammalian STE20-like protein kinase 2 ... 的相關結果
Aim Mammalian STE20-like protein kinase 2 (MST2) plays an important role in apoptosis and the development of many disorders. ... <看更多>
mst2 gene 在 Mst1/Mst2 Regulate Development and Function of Regulatory ... 的相關結果
All mice except for B6.SJL and Rag1 −/− from the Jackson Laboratory were maintained on a 129/Sv genetic background and raised in a specific pathogen–free ... ... <看更多>
mst2 gene 在 Differential localization of A-Raf regulates MST2-mediated ... 的相關結果
In addition, KSR2 regulates genes controlling adipocyte differentiation in white adipose tissue and is crucial for 1,25-dihydroxyvitamin D3- ... ... <看更多>
mst2 gene 在 STK3 protein expression summary 的相關結果
STK3 (KRS1, MST2) · Enzymes Plasma proteins · Evidence at protein level (all genes). ... <看更多>
mst2 gene 在 Demystifying MST Family Kinases in Cell Death 的相關結果
MST1 and MST2 (herein called MST) and touch upon the roles of their orthologs across ... through the transcription of cell death genes, such as bim [28]. ... <看更多>
mst2 gene 在 Hippo Pathway-related Genes Expression Is Deregulated in ... 的相關結果
The Hippo signaling cascade is composed of MST1/MST2,. SAV1, LATS1/LATS2, MOB1A/MOB1B, YAP and TAZ proteins. Activation of the classical pathway ... ... <看更多>
mst2 gene 在 MST2 Protein, active, 250 µg | 14-524M 的相關結果
MST2 Protein, active, 250 µg Active, N-terminal His6-tagged recombinant human ... Entrez Gene Summary, Protein kinase activation is a frequent response of ... ... <看更多>
mst2 gene 在 MST1/Hippo promoter gene methylation predicts poor ... - IFCT 的相關結果
the Drosophila melanogaster Hippo gene, and MST2 (STK3) are the best characterised of the five MST kinases (MST1/2/3/4 and YSK1) existing in mammals. ... <看更多>
mst2 gene 在 Mammalian Mst1 and Mst2 Kinases Play Essential Roles in ... 的相關結果
aGenetic Disease Research Branch, National Human Genome Research Institute, Bethesda, MD 20892; bDepartments of Developmental Biology and. ... <看更多>
mst2 gene 在 Phospho-MST1 (Thr183)/MST2 (Thr180) (E7U1D) Rabbit mAb 的相關結果
Monoclonal Antibody for studying MST1 (Thr183) phosphate/MST2 (Thr180) phosphate. Cited in 50 publications. ... Entrez-Gene Id: 6789 , 6788. ... <看更多>
mst2 gene 在 The Mst1 and Mst2 kinases control activation of rho family ... 的相關結果
... of the Mst2 gene in the entire hematopoietic lineage. These mice were born at a normal ratio and survived weaning without difficulty. ... <看更多>
mst2 gene 在 Gene: STK3 (ENSG00000104375) - Summary - Homo_sapiens 的相關結果
serine/threonine kinase 3 [Source:HGNC Symbol;Acc:HGNC:11406]. Gene Synonyms. KRS1, MST2. Location. Chromosome 8: 98,371,228-98,942,827 reverse strand. ... <看更多>
mst2 gene 在 Targeted disruption of the Mst1 and Mst2 genes. (A) Structures ... 的相關結果
To further explore the physiological func- tions of Mst kinases in mice, we targeted the murine Mst1 and Mst2 genes by homologous recombination in ES cells, ... ... <看更多>
mst2 gene 在 Inhibition of Hippo tumor suppressors MST1/2 slows prostate ... 的相關結果
To assess if MST1 and/or MST2 play a role in PC proliferation, pharmacological and genetic studies were carried out across varying PC cell ... ... <看更多>
mst2 gene 在 Hippo Signal Transduction Mechanisms in T Cell Immunity 的相關結果
Also, germline deletion of Mst1 and Mst2 genes (but not each single gene) causes embryonic death due to developmental defects (2, 4). ... <看更多>
mst2 gene 在 Fig S1 genotyping - Caltech AUTHORS 的相關結果
A. Rassf1a knockout mice lack exon 1 of the Rassf1 gene. ... DNA methylation analysis of the Mst1 and Mst2 genes in human liver cancer specimens. ... <看更多>
mst2 gene 在 Hippo Kinases Mst1 and Mst2 Sense and Amplify IL 的相關結果
IL-2 Target Gene Expression and STAT5 Activation Are Reduced in Mst1–Mst2-Deficient Treg Cells. (A) Number of differentially expressed genes (> 0.5 log2 ... ... <看更多>
mst2 gene 在 Phospho-MST1 (Thr183)/MST2 (Thr180) antibody (CL488 ... 的相關結果
MST1 and its closest paralogs MST2 (encoded by the STK3 gene), MST3, and MST4 are members of the Class II Germinal Center Family of Protein Kinases . STK3/4 and ... ... <看更多>
mst2 gene 在 Defining Driver DNA Methylation Changes in Human Cancer 的相關結果
These changes include a globally hypomethylated tumor cell genome and ... Deletion of the MST1/MST2 genes or overexpression of YAP produces ... ... <看更多>
mst2 gene 在 A comprehensive evaluation of Hippo pathway silencing in ... 的相關結果
Treatment with MG132 demonstrated an accumulation of MST2 in 25% of sarcoma cell ... Evaluation of 259 sarcomas in The Cancer Genome Atlas ... ... <看更多>
mst2 gene 在 Extracellular matrix stiffness regulates degradation of ... - bioRxiv 的相關結果
Silencing of STK3, the gene encoding MST2, resulted in increased nucleus/cytoplasm ratio of YAP in physiological (Low) and breast-tumor ... ... <看更多>
mst2 gene 在 Rapid epigenetic adaptation to uncontrolled heterochromatin ... 的相關結果
Chromatin is classified into euchromatin, which is gene rich and actively ... inactivation of essential genes, suggesting that Mst2 and Epe1 ... ... <看更多>
mst2 gene 在 MST2 Antibody 3952S from Cell Signaling Technology 的相關結果
... HostRabbit; NCBI Gene AliasesKRS1, MST2; NCBI Full Gene Nameserine/threonine kinase 3; ClonalityPolyclonal; Research AreaApoptosis; Molecular Weight60. ... <看更多>
mst2 gene 在 GSAR: Gene Set Analysis in R - Bioconductor 的相關結果
2014 that MST2 can be used as a graphical visualization tool to highlight the most highly correlated genes in the correlation network. A gene that is highly. ... <看更多>
mst2 gene 在 Showing Protein Serine/threonine-protein kinase 3 ... 的相關結果
MST-2 ; Mammalian STE20-like protein kinase 2; STE20-like kinase MST2; Serine/threonine-protein kinase Krs-1. Gene Name, STK3. Protein Type, Unknown. ... <看更多>
mst2 gene 在 MST2 Protein, active, 10 µg | 14-524 - Millipore Sigma 的相關結果
MST2 Protein, active, 10 µg Active, N-terminal His6-tagged recombinant human ... Entrez Gene Summary, Protein kinase activation is a frequent response of ... ... <看更多>
mst2 gene 在 Crucial Role for Mst1 and Mst2 Kinases in Early Embryonic ... 的相關結果
Mammalian sterile 20-like kinases 1 and 2 (Mst1 and Mst2, respectively) are ... Mst2 mutant mice showed that mice containing a single copy of either gene ... ... <看更多>
mst2 gene 在 Anti-MST1 (phospho Thr183) / MST2 (phospho ... - GeneTex 的相關結果
Rabbit Polyclonal MST1 (phospho Thr183) / MST2 (phospho Thr180) antibody. Validated in WB, IHC-P. Tested in Human, Mouse, Rat. ... <看更多>
mst2 gene 在 Proteasomal down-regulation of the proapoptotic MST2 ... 的相關結果
This tumour type is characterised by a high frequency of genetic mutations within the RAS-RAF-MEK-ERK pathway, with mutations in BRAF, ... ... <看更多>
mst2 gene 在 The mammalian Ste20-like kinase 2 (Mst2 ... - ORBilu 的相關結果
An initial genetic study in mitral valve prolapse patients revealed an association between a polymorphism in the human MST2 gene and adverse cardiac ... ... <看更多>
mst2 gene 在 STK3 (serine/threonine kinase 3) | Gene Report - BioGPS 的相關結果
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. ... <看更多>
mst2 gene 在 MST2 kinase suppresses rDNA transcription in response to ... 的相關結果
MST2 localizes in the nucleolus and interacts with nucleolar chromatin ... The genetic loci encompassing the ribosomal genes (rDNA) are the ... ... <看更多>
mst2 gene 在 Recombinant human MST2/STK3 protein - NKMAX BIO 的相關結果
Description. STK3, also known as serine/threonine-protein kinase 3, is a mammalian Ste20-related protein kinases most closely related to Drosophila Hippo, ... ... <看更多>
mst2 gene 在 Phoenix open tv schedule 的相關結果
... are Mark Calcavecchia, Gene Littler, Phil Mickelson, and Arnold Palmer. ... AM MST: 1:00 PM MST: 2 hrs: GOLF: 2/11/2023: Saturday: WM Phoenix Open 2023: ... ... <看更多>
mst2 gene 在 The Fungal Kingdom - Google 圖書結果 的相關結果
The gene MST2 is highly expressed in arbuscules and intercellular hyphae. The high affinity and transport capability for xylose residues suggest that the ... ... <看更多>
mst2 gene 在 Macromolecular Anticancer Therapeutics - 第 51 頁 - Google 圖書結果 的相關結果
Moreover, targeted disruption of individual raf genes in the mouse has ... MST-2 is a kinase, which is activated by pro-apoptotic agents such as ... ... <看更多>
mst2 gene 在 Telephone Directory: 1973 - 第 59 頁 - Google 圖書結果 的相關結果
... ទ : គ្ន ” “ ឥ ® ដ្ឋ និ 6423 3226 GENE HRW GFM 72100 7132B GFCP GLGL 8102 4210 HA ACA N 4231 TAD S OSBORN JAMES C CDR . ... NORWEB R H MST2 . ... <看更多>
mst2 gene 在 A Hippo's View: From Molecular Basis to Translational Medicine 的相關結果
... results in the phosphorylation of core Ste20-like kinases MST1 and MST2 (MST1/2), ... Surprisingly, the association between Hippo pathway target gene ... ... <看更多>
mst2 gene 在 Disease and the Hippo Pathway: Cellular and Molecular Mechanisms 的相關結果
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular ... KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in ... ... <看更多>
mst2 gene 在 The Hippo Signaling Pathway and Cancer - 第 68 頁 - Google 圖書結果 的相關結果
Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic ... Oka T, Mazack V, Sudol M. Mst2 and Lats kinases 68 M. Sudol et al. ... <看更多>
mst2 gene 在 Molecular Oncology - 第 269 頁 - Google 圖書結果 的相關結果
Effects of ras and von Hippel-Lindau (VHL) gene mutations on ... Mutant K-Ras activation of the proapoptotic MST2 pathway is antagonized by wild-type K-Ras. ... <看更多>
mst2 gene 在 Insights in Renal Pharmacology: 2021 - 第 44 頁 - Google 圖書結果 的相關結果
Two forms of ST2: transmembrane (mST2) and soluble isoforms (sST2) have been ... antibodies or by gene knockout approaches by several investigators. ... <看更多>
mst2 gene 在 Neues historisch-biographisches Lexikon der Tonkünstler: A-D 的相關結果
38 ) Wladimir , Fürst von Nowogrod Oper in 3 Akt . 39 ) Der betro : gene Betrüger . ... Mst . 2 ) Motetto : In se- rena coeli scena etc. a A. solo , c . ... <看更多>
mst2 gene 在 MST2/STK3 Kinase Assay Service - Reaction Biology 的相關結果
CAT#. MST2/STK3 ; Enzyme. Human MST2/STK3 ; HGNC. STK3 ; Synonym. MST2, KRS1 ; Substrates. MBP (Myelin Basic Protein), 20 µM. ATP 10 µM. ... <看更多>
mst2 gene 在 STK3 Gene - GeneCards | STK3 Protein | STK3 Antibody 的相關結果
STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), ... ... <看更多>