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#1. 傳統與新一代口服抗血小板藥物P2Y12接受體抑制劑於東亞人種 ...
口服抗血小板藥物P2Y12接受體抑制劑,一般在急性冠心症或支架置放術後合併阿斯匹靈使用;傳統P2Y12接受體抑制劑為「保栓通(clopidogrel;商品名plavix)」,新一代的 ...
2. Sibbing D, Orban M; Massberg S. Potent P2Y12 receptor inhibitors in patients with acute coronary syndrome. Hä- mostaseologie 2013; 33: 9-15.
所得出的結論為DAPT (Aspirin + 一種ADP P2Y12 inhibitor: clopidogrel、prasugrel、 ticagrelor) 可有效降低PCI 後支架血栓與後續的心血管事件,此外Aspirin 應使用低.
#4. Antiplatelet drugs - P2Y12 inhibitors - MedlinePlus
Antiplatelet drugs - P2Y12 inhibitors · Aspirin is an antiplatelet drug that may be used. · P2Y12 receptor blockers are another group of ...
P2Y12 inhibitors[edit] ... The drugs clopidogrel (Plavix), prasugrel (Efient, Effient), ticagrelor (Brilinta), and cangrelor (Kengreal) bind to this receptor and ...
#6. P2Y12 platelet inhibition in clinical practice - NCBI
Thienopyridines inhibit the platelet activation and aggregation by antagonizing the platelet P2Y12 receptor. This prevents the binding of ADP to ...
#7. International Expert Consensus on Switching Platelet P2Y 12 ...
Clopidogrel, prasugrel, and ticagrelor are the most commonly used oral platelet P2Y12 inhibitors; the use of ticlopidine, the first available ...
#8. 2020 APSC Recommendations on use of P2Y12 inhibitors in ...
Newer generation P2Y12 inhibitors (i.e. ticagrelor and prasugrel) have demonstrated improved clinical outcomes compared with clopidogrel.
#9. P2Y12 inhibitors: differences in properties and mechanisms of ...
The thienopyridines (ticlopidine, clopidogrel, and prasugrel) are indirectly acting platelet inhibitors where the active metabolites of the thienopyridine ...
#10. Monotherapy with a P2Y 12 inhibitor or aspirin for secondary ...
Antiplatelet therapy is recommended among patients with established atherosclerosis. We compared monotherapy with a P2Y12 inhibitor versus ...
#11. P2Y12 inhibitor monotherapy or dual antiplatelet therapy after ...
P2Y12 inhibitor monotherapy or dual antiplatelet therapy after coronary revascularisation: individual patient level meta-analysis of randomised ...
#12. Assessment of Pretreatment With Oral P2Y12 Inhibitors and ...
This systematic review and meta-analysis assesses the association between oral P2Y12 inhibitor pretreatment and cardiovascular and bleeding ...
#13. Purinergic P2Y12 Receptor - an overview | ScienceDirect Topics
The P2Y12 inhibitors include clopidogrel, prasugrel, ticagrelor, and cangrelor. Patients who have cardiovascular problems are usually prescribed combined P2Y12 ...
#14. P2Y12 Inhibitor Monotherapy after Percutaneous Coronary ...
Dual antiplatelet therapy (DAPT) with aspirin plus a P2Y12 inhibitor for 6-12 months is the current standard treatment for patients after percutaneous ...
#15. P2Y12 inhibitors - Straight Healthcare
P2Y12 INHIBITORS · Clopidogrel (Plavix®). No dosage adjustment is necessary in patients with liver disease · Prasugrel (Effient®). Child-Pugh A/B: No dosage ...
#16. A brief review on resistance to P2Y12 receptor antagonism in ...
Platelet inhibition is important for patients with coronary artery disease. When dual antiplatelet therapy (DAPT) is required, a P2Y12- ...
#17. P2Y12 inhibitors during and after acute coronary syndrome ...
P2Y12 platelet adenosine diphosphate receptor inhibitors in combination with aspirin have significantly reduced the mortality and morbidity of patients after ...
#18. P2Y12 inhibitors for the neurointerventionalist
The use of antiplatelets is widespread in clinical practice. However, for neurointerventional procedures, protocols for antiplatelet use are ...
#19. A Genotype-Guided Strategy for Oral P2Y 12 Inhibitors in ...
... primary percutaneous coronary intervention (PCI) benefit from genotype-guided selection of oral P2Y12 inhibitors. Methods We conducted .
#20. P2Y12 Inhibitor Monotherapy with Clopidogrel versus ... - MDPI
Background: P2Y12 inhibitor monotherapy is an alternative antiplatelet strategy in patients undergoing percutaneous coronary intervention (PCI).
#21. Efficacy and safety of newer P2Y12 inhibitors for acute ...
We compared the effect of P2Y12 inhibitors on clinical outcomes in patients with acute coronary syndrome (ACS). Randomized controlled trials ...
#22. Impact of Implementing CYP2C19 Genotype-Guided ...
Ticagrelor was recommended for patients with a LOF allele. Factors related to P2Y12 inhibitor selection were determined by logistic regression.
#23. Timing of Oral P2Y 12 Inhibitor Administration in Patients With ...
Abstract Background Although oral P2Y12 inhibitors are key in the management of patients with non–ST-segment elevation acute coronary ...
#24. Oral P2Y12 Inhibitors in Acute Coronary Syndrome - American ...
Randomized trials investigating oral P2Y12 inhibitors clopidogrel, prasugrel, or ticagrelor in ACS patients and extending beyond 30-day follow- ...
#25. P2Y12-inhibitors in NSTEMI - old and new guidelines
P2Y12 -inhibitors in NSTEMI - old and new guidelines. Association for Acute CardioVascular Care webinar. Tuesday, 16 February 2021 from 18:00 to 19:00 CET.
#26. P2Y12 Receptor Inhibitors in Acute Coronary Syndromes
The P2Y12 receptor plays a pivotal role in platelet activation and aggregation through a complex cascade of actions.
#27. P2Y12 inhibitors in acute coronary syndrome: when to give th...
New and more powerful P2Y12 receptor inhibitors have been introduced, as well as first and then second-generation drug-eluting stents (DES), ...
#28. Injectable P2Y12 Inhibitor Selatogrel Shows Promise in Acute MI
The novel reversible P2Y12 inhibitor selatogrel (Idorsia Pharmaceuticals), administered via subcutaneous injection, is safe and causes a rapid ...
#29. Aspirin and a PoTent P2Y12 Inhibitor Versus Aspirin and ...
Dual antiplatelet therapy with a P2Y12 inhibitor plus aspirin will be given according to the allocated arms in patients undergoing elective ...
#30. Genotype-guided treatment of oral P2Y12 inhibitors - Future ...
P2Y12 inhibitor · prasugrel · ticagrelor. Dual antiplatelet therapy, consisting of aspirin and a P2Y12 inhibitor, remains the cornerstone of ...
#31. P2Y12 inhibitor loading dose before catheterization in ST ...
P2Y12 inhibitor loading dose before catheterization in ST-segment elevation myocardial infarction: Is this the best strategy? Dose de carga do inibidor P2Y12 ...
#32. Comparative Effectiveness and Safety of Oral P2Y12 Inhibitors ...
Although oral P2Y12 inhibitors (P2Y12-Is) are one of the most commonly prescribed medication classes in patients with end stage kidney ...
#33. P2Y12 Inhibitor Monotherapy Versus Conventional Dual ...
Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor is the cornerstone of treatment after percutaneous coronary intervention ( ...
#34. P2Y12 Inhibitor Use Linked With Reduced Microcirculatory ...
The researchers noted that all patients were preloaded before primary PCI with 300 mg aspirin plus 600 mg clopidogrel, 180 mg ticagrelor, or 60 ...
#35. De-escalation of P2Y12 Inhibitor Use After Percutaneous ...
De-escalation from potent platelet P2Y12 inhibitors to clopidogrel is common. Despite having a clinical rationale, non-bleeding-related ...
#36. Third-Generation P2Y12 Inhibitors in East Asian Acute ...
Request PDF | Third-Generation P2Y12 Inhibitors in East Asian Acute Myocardial Infarction Patients: A Nationwide Prospective Multicentre Study ...
#37. P2Y12 Platelet Function Test | MLabs
Automated platelet induced aggregation. ... To determine the degree of platelet inhibition from the use of P2Y12 inhibition drug therapies known as ...
#38. P2Y12 inhibition in STEMI: early, strong or both?
P2Y12 inhibition in STEMI: early, strong or both? EuroIntervention 2018;14:25-27. DOI: 10.4244/EIJV14I1A3. Fabio Mangiacapra, MD, PhD; Germano Di Sciascio*, ...
#39. Full article: Selatogrel, a novel P2Y12 inhibitor: a review of the ...
Platelet P2Y12 inhibitors have a key role in reducing thrombotic complications in patients undergoing percutaneous coronary intervention (PCI) and those ...
#40. Laboratory monitoring of P2Y 12 inhibitors - Wiley Online Library
Monitoring P2Y12 inhibition for the purpose of guiding the intensity of antiplatelet therapy is not recommended. IIb, B, [8–10,24]. Monitoring ...
#41. P2Y12 Platelet Inhibitor | DrugBank Online
A P2Y12 platelet receptor antagonist used during percutaneous coronary intervention to reduce the risk for periprocedural myocardial infarction (MI), repeat ...
#42. Safety of Oral P2Y12 Inhibitors in Interventional Neuroradiology
In the field of interventional neuroradiology, oral P2Y12 inhibitors are used in combination with aspirin for dual-antiplatelet therapy.
#43. P2Y12 Receptor Inhibitors - YouTube
#44. Genotype-guided strategy to select oral P2Y12 inhibitor in ...
P2Y12 inhibitors ticagrelor and prasugrel are stronger platelet inhibitors than clopidogrel, and they lead to less stent thrombosis (80% MI and ...
#45. New Guidance on Switching Between P2Y12 Inhibitors
One of the main treatment modalities in patients with ACS and for those undergoing percutaneous coronary intervention (PCI) are P2Y12 inhibitors ...
#46. Timing of Oral P2Y12 Inhibitor Administration in Patients With ...
Although oral P2Y12 inhibitors are key in the management of patients with non-ST-segment elevation acute coronary syndrome, the optimal timing ...
#47. Assessment of P2Y12 inhibitor usage and switching in acute ...
The strategy of utilizing a newer P2Y12 inhibitor and then switching to clopidogrel in ACS patients following PCI is used with some ...
#48. Which P2Y12 inhibitor is preferred in non-ST-elevation acute ...
Class IIa After coronary stent implantation in the setting of ACS, ticagrelor is preferred over clopidogrel for maintenance P2Y12 inhibitor therapy.
#49. HelixTalk Episode #105 - Unraveling the Mystery of P2Y12 ...
In this episode, we review the three oral P2Y12 inhibitors on the market (clopidogrel, prasugrel, ticagrelor) and discuss each agent's ...
#50. P2Y12 Inhibitor Assay - Test Guide | Waikato DHB Laboratory ...
Normal individual not taking P2Y12 180-376 PRU Evidence of P2Y12 receptor blockade <180 PRU Appropriate response to anti-platelet therapy for cardiology ...
#51. Intolerance to Multiple P2Y12 Inhibitors Following ... - Cureus
Dual antiplatelet therapy (DAPT), defined as administration of a P2Y12 receptor inhibitor (clopidogrel, prasugrel, or ticagrelor) and ...
#52. The comparative effectiveness, safety, value, and adherence ...
Background P2Y12 inhibitors are a class of medications indicated with aspirin as part of dual antiplatelet therapy (DAPT) for patients with acute coronary ...
#53. A look at the interaction between opioids and oral P2Y12 ...
Cardiology Today | A recently recognized drug-drug interaction between opioids and P2Y12 inhibitors may have clinical implications for ...
#54. After PCI and short-term DAPT, P2Y12 inhibitors alone vs ...
In patients who received short-term dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI), does P2Y12 inhibitor ...
#55. P2Y12 inhibitors for acute coronary syndromes - Dove ...
Dual-antiplatelet therapy involving an oral P2Y12 inhibitor plus ... Keywords: P2Y12 inhibitors, acute coronary syndrome, ticagrelor, ...
#56. Clopidogrel resistance and clopidogrel treatment failure
The indications for P2Y12 inhibitor use for the treatment of coronary ... The extent of P2Y12 inhibition by clopidogrel in diabetes mellitus ...
#57. Coagulation | Plavix VerifyNow Platelet Reactivity (PRU) Test
This test measures the extent of platelet aggregation in the presence of P2Y12 inhibitor drugs such as clopidogrel (Plavix), prasugrel (Effient), ticagrelor ( ...
#58. incidence and rationale for p2y12 inhibitor switching in ...
Dual antiplatelet therapy (DAPT), with aspirin and a P2Y12 inhibitor, is the standard therapy for patients with acute coronary syndrome (ACS) or after ...
#59. Powerful P2Y12 inhibition after percutaneous coronary ...
Powerful P2Y12 inhibition after percutaneous coronary intervention for an acute coronary syndrome: “the times they are a changing”
#60. Impaired aspirin-mediated platelet function inhibition in ...
Aspirin- and P2Y12-mediated platelet inhibition is impaired in resuscitated patients treated with therapeutic hypothermia. On day 3, we recorded ...
#61. Benefits and risks of P2Y12 inhibitor preloading in patients ...
Treatment with P2Y12 inhibitors is an integral part of the standard of care for patients undergoing percutaneous coronary intervention.
#62. Comparative Gastrointestinal Bleeding Risks of the P2Y 12 ...
The P2Y12 inhibitors (formerly thienopyridines) are a class of antiplatelet agents associated with gastrointestinal (GI) bleeding, ...
#63. Platelet Inhibition With the P2Y12 Inhibitor Cangrelor - HMP ...
Think of the P2Y12 receptor as being shaped like a crown. If you drop a ball into the central part of the crown, that is the ADP site of the ...
#64. The opioid-P2Y 12 inhibitor interaction: Potential strategies to ...
This review characterizes the mechanism of the opioid-P2Y12 inhibitor interaction, strategies aimed at mitigating the interaction and appraises promising ...
#65. Efficacy of P2Y12 Receptor Blockers After Myocardial ...
Background: Various antiplatelet drugs are used following Acute Coronary Syndromes (ACS). Of them, adenosine diphosphate receptor P2Y12 inhibitors clopidogrel, ...
#66. Reversal Strategy For Antagonizing The P2Y12-Inhibitor ...
However, there is no experience or recommendation how to antagonize the reversible and highly effective P2Y12-inhibitor ticagrelor and how ...
#67. Therapy with ASA, P2Y12 inhibitor, and statin at discharge ...
Patients undergoing PCI who receive prescriptions for all medications (ASA, P2Y12 and statins) for which they are eligible for at discharge.
#68. Clopidogrel, a Platelet P2Y12 Receptor Inhibitor, Reduces ...
Clopidogrel, a Platelet P2Y12 Receptor Inhibitor, Reduces Vascular Inflammation and Angiotensin II Induced-Abdominal Aortic Aneurysm Progression.
#69. P2Y12 Inhibitor Preloading Before PCI Associated With a ...
Loading of third-generation P2Y12 inhibitors before primary percutaneous coronary intervention for ST-segment elevation myocardial ...
#70. Expert Opinion on P2Y12 Inhibitors Use in Management of ...
Ticagrelor is a potent, oral P2Y12 inhibitor used as a part of dual antiplatelet therapy (DAPT) in acute coronary syndromes (ACS). New evidence has emerged ...
#71. P2Y12 receptor inhibitors สำหรับการป้องกัน atherothrombosis ...
ยากลุ่ม P2Y12 receptor inhibitors เป็นยาต้านการเกาะกลุ่มของเกล็ดเลือดที่ค่อนข้างใหม่และยังได้รับการพัฒนามาอย่างต่อเนื่อง ...
#72. Modern therapy of acute coronary syndromes based on ...
-antiplatelet therapy, a combination of acetylsalicylic acid and a P2Y12 inhibitor. The preferred P2Y12 inhibitors are pra- sugrel or ticagrelor.
#73. FULLTEXT01.pdf - DiVA portal
A high level of platelet inhibition was rapidly achieved in patients who were not receiving an oral P2Y12 inhibitor. Both doses of selatogrel ...
#74. 2 Switching therapy - Canadian Cardiovascular Society
In-hospital switching of oral P2Y12 inhibitor treatment in patients with acute coronary syndrome undergoing percutaneous coronary intervention: prevalence, ...
#75. Clinical Challenges: Back to Square One in Anticoagulation ...
The intravenous direct thrombin inhibitor could help patients achieve ... heparin plus a newer P2Y12 inhibitor such as cangrelor (Kengreal), ...
#76. JAHA:P2Y12受体抑制剂之辩,东亚与欧美的最新博弈
P2Y12受体抑制剂,氯吡格雷还是替格瑞洛? ... Safety and Effectiveness of Contemporary P2Y12 Inhibitors in an East Asian Population With Acute ...
#77. Effect of P2Y12 inhibitors on inflammation and immunity.
Platelet P2Y12 inhibitors form a major part of the treatment strategy for patients with acute coronary syndromes (ACS) due to the importance ...
#78. P2Y12/PRU "Plavix Effect" Assay - RK.md
P2Y12 receptor inhibitors like clopidogrel (Plavix), prasugrel (Effient), and ticagrelor (Brilinta) are powerful antiplatelet agents to ...
#79. Platelets in Thrombotic and Non-Thrombotic Disorders: ...
P2Y12 inhibitors are broadly used worldwide to prevent and treat ischemic ... P2Y12 inhibitor, ticagrelor, and the intravenous P2Y12 receptor inhibitor ...
#80. Antiplatelet Medications - Summary Table Aspirin - GrepMed
... A2 • Acute coronary syndrome (in combination with P2Y12 inhibitor and ... to anticoagulation in a-fib P2Y12 Inhibitors (clopidogrel, ...
#81. Mount Sinai Expert Guides: Critical Care - 第 131 頁 - Google 圖書結果
... Aspirin 162–325 mg followed by 81 mg daily P2Y12 inhibitors • Clopidogrel ... by 4 μg/kg/min continuous infusion A P2Y12 inhibitor should be continued ...
#82. The ESC Textbook of Intensive and Acute Cardiovascular Care
There is limited evidence in regard to when the P2Y12 inhibitor should be initiated in STEMI patients. The Administration of Ticagrelor in the Cath Lab or ...
#83. Recommendations for perioperative P2Y12 inhibitor ...
Dual antiplatelet therapy (DAPT) with ASA and P2Y12-receptor inhibitors (clopidogrel, ticagrelor and prasugrel) (Table) reduces the risk for ...
#84. Critical Care Medicine: Principles of Diagnosis and ...
A loading dose of a P2Y12 receptor inhibitor should be given to patients undergoing PCI with stenting. Options include the following: a.
#85. Interventional Cardiology: Principles and Practice
Current guideline recommendations are to give a loading dose of a P2Y12 inhibitor (i.e., clopidogrel 600mg, prasugrel 60mg, ticagrelor 180mg) prior to PCI ...
#86. Updates in Percutaneous Coronary Intervention, An Issue of ...
900 mg.80 P2Y12 inhibitors prevent platelet activation through the inhibition of adenosine diphosphate receptors and are also indicated in all patients ...
#87. better or worse than P2Y12 inhibitors Giuseppe Biondi Zoccai
Novel antithrombotic agents in acute coronary syndromes: better or worse than P2Y12 inhibitors Giuseppe Biondi Zoccai Sapienza Università di Roma. Published by ...
#88. Antiplatelet Agents—Advances in Research and Application: ...
Newly developed P2Y12 inhibitors are more potent, more predictable, ... Ticagrelor is a direct-acting and reversible inhibitor of the P2Y12 receptor with ...
#89. Focus on Prasugrel, Ticagrelor, Cangrelor and Elinogrel - 블로그
Update on novel P2Y12 inhibitors: Focus on Prasugrel, Ticagrelor, ... thienopyridines - platelet ADP-P2Y12 receptor의 첫번째 inhibiting drug.
#90. Angela O'Neill, Author at Cardiac Rhythm News
TCT 2019: Apixaban plus a P2Y12 inhibitor is the optimal strategy... 4th October 2019. Stephan Windecker presents preferred strategies with Apixaban.
#91. Star Update Podcast - Cardiology News Summaries - Anchor
The investigational PCSK9 inhibitor of Merck, MK-0616 — comes in pill form, ... course of Dual Anti-Platelet Therapy followed by P2Y12 inhibitor monotherap.
#92. Desenvolvimento de mercado trombose Drogas por receita ...
Plaquetário P2Y12 Inhibitor Outras por indicação. Embolia pulmonar. Fibrilação atrial. Trombose venosa profunda
#93. Thrombosis Drugs Market – Which Companies to Lead the ...
P2Y12 Platelet Inhibitor, Factor Xa Inhibitor, Heparin By Application : Deep Vein Thrombosis, Pulmonary Embolism, Atrial Fibrillation
#94. Fármacos contra la trombosis Mercado - Influencers Web
P2Y12 Platelet Inhibitor Others. Indication. Pulmonary Embolism Atrial Fibrillation Deep Vein Thrombosis Others. Distribution Channel.
#95. Fármacos contra la trombosis Mercado - El Diario de Hermosillo
P2Y12 Platelet Inhibitor Others. Indication. Pulmonary Embolism Atrial Fibrillation Deep Vein Thrombosis Others. Distribution Channel.
p2y12 inhibitor 在 P2Y12 Receptor Inhibitors - YouTube 的推薦與評價
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