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詳情:https://www.sundaymore.com/911405/
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1. “Oral Supplementation of Specific Collagen Peptides Has Beneficial Effects on Human Skin Physiology: A Double-Blind, Placebo-Controlled Study”, Skin Pharmacol Physiology, Aug 2013
2. “Oral Intake of Specific Bioactive Collagen Peptides Reduces Skin Wrinkles and Increases Dermal Matrix Synthesis”, Skin Pharmacol Physiology, Dec 2013
同時也有2491部Youtube影片,追蹤數超過6萬的網紅Herman Yeung,也在其Youtube影片中提到,Note download 筆記下載 : https://hermanutube.blogspot.hk/2016/01/youtube-pdf.html -----------------------------------------------------------------------...
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human physiology 在 可貓all cat Facebook 的最讚貼文
疫情嚴重,注意健康,加油
2019-2020相關資料文獻整理
#新型冠狀病毒和黑種草油的科學研究
2019-nCoV & Nigella Sativa Science
Researches
#林博士聲明: 2020.01.28
1.本文為本人整理編寫的原創文獻醫學文稿,重要內容均注明原文出處(或網路連結)若有疏漏,敬請指正。
(一)#抗病毒作用-正義單鏈RNA病毒
Antiviral effect-positive and single stranded RNA virus
- 2019新型冠狀病毒(Novelcoronavirus),世界衛生組織命名縮寫為2019-nCoV、武漢肺炎(Wuhanpneumonia)等。2019新型冠狀病毒與2003年4月在亞洲爆發SARS,SARS-CoV都是正義單鏈RNA病毒(positivesinglestrandedRNAvirus),這類病毒還包括人類的C型肝炎病毒(HepacivirusC)。
黑種草油(子)迄今並無抗冠狀病毒的研究。但臨床研究顯示黑種草油可以抗C型肝炎病毒(30名C肝病患),降低體內病毒載量。
埃及30名患有C型肝炎病毒(HCV)感染患者,未經甲型干擾素(α-Interferon)治療,每天餐後食用黑種草油,每日3次,連續服用3個月後,可顯著改善HCV病毒載量(380808.7±610937vs147028.2±475225.6,P=0.001)和提高體內總抗氧化能力TAC(1.35±0.5vs1.612±0.56, P=0.001),與下列實驗室參數得到改善:總氮蛋白、白蛋白、紅血球細胞數、血小板計數和下肢水腫等臨床狀況指數。
1.Barakat, EmanMahmoud Fathy, Lamia Mohamed El Wakeel, and RadwaSamir Hagag. "Effects of Nigella sativa on outcome of hepatitis C in Egypt." World journal of gastroenterology: WJG 19.16 (2013): 2529.
2.Oyero, OlufunmilayoG., et al. "Selective inhibition of hepatitis c virus replication by Alpha-zam, a Nigella sativa seed formulation." African journal of traditional, complementary and alternative medicines 13.6 (2016): 144-148.
(二) #免疫調節-提高巨噬細胞和樹突狀細胞作用.
*Immunomodulatory effects
- 研究顯示:黑種草油或其活性成分百里醌(TQ,Thymoquinone)可以調節免疫力(Th1和Th2),提高巨噬細胞(macrophage)和樹突狀細胞(dendriti)作用,顯示出有效的抗發炎作用。
黑種草油可增加吞噬活性(吞噬率56.83±6.37%)和吞噬指數(5.18±0.39),巨噬細胞分泌IL-12(最高水平在66.33±2.11μM)和TLR4的表達。數據通過單因子變異數分析(One-wayANOVA)進行統計學檢驗,顯著性為95%。
1.Akrom, Akrom, and MustofaMustofa. "Black cumin seed oil increases phagocytic activity and secretion of IL-12 by macrophages." Biomedical Research 28.12 (2017): 5241-5246.
2.Finlay, Trisha M., et al. "Thymoquinone-induced Neu4 sialidase activates NFκB in macrophage cells and pro-inflammatory cytokines in vivo." Glycoconjugate journal 27.6 (2010): 583-600.
3.Salem, Mohamed Labib. "Immunomodulatory and therapeutic properties of the Nigella sativa L. seed." International immunopharmacology 5.13-14 (2005): 1749-1770.
(三) #善肺部發炎症狀和損傷
Improve lung inflammation and injury
- 動物研究顯示:黑種草和其提取物或百里醌(TQ)對氣管反應和肺部炎症有預防作用,黑種草油可顯著降低因高氧吸入引起的肺損傷。
●黑種草的百里醌(TQ,thymoquinone)治療致敏組動物,可顯著善其肺部病理變化,降低其IL-4水平(p<0.05至p<0.001),增加其IFN-γ水平(p<0.001)。
●黑種草治療可抑制炎症性肺反應,顯著降低(p<0.05)支氣管周炎性細胞浸潤、肺泡中隔浸潤、肺泡水腫 肺泡滲出液、肺泡巨噬細胞和間質纖維化,肉芽腫和壞死形成。
●在組織病理學和免疫化學評估中,高氧+ 黑種草組的肺損傷嚴重程度明顯降低(P <.05),GSH-Px(穀胱甘肽氧化物酶)和SOD(超氧化物歧化酶)水平得到顯著保留MDA(血清脂質過氧化物)和MPO(骨髓過氧化酶)水平顯著低(P <.05)。
1.Boskabady,MohammadHossein,etal."TheeffectofNigellasativaextractontrachealresponsivenessandlunginflammationinovalbumin-sensitizedguineapigs."Clinics66.5(2011):879-887.
2.Keyhanmanesh,Rana,etal."Effectofthymoquinoneonthelungpathologyandcytokinelevelsofovalbumin-sensitizedguineapigs."Pharmacologicalreports62.5(2010):910-916.
3.Kanter,Mehmet."EffectsofNigellasativaseedextractonamelioratinglungtissuedamageinratsafterexperimentalpulmonaryaspirations."Actahistochemica111.5(2009):393-403.
4.Tayman,Cuneyt,etal."ProtectiveeffectsofNigellasativaoilinhyperoxia-inducedlunginjury."ArchivosdeBronconeumología(EnglishEdition)49.1(2013):15-21.
(四) #解呼吸道發炎症狀
Relief the symptoms of respiratory tract infection
- 多篇人體臨床研究:黑種草油可顯著緩解咽喉炎或扁桃腺炎的咽喉腫痛,補充黑種草油可改善哮喘和肺功能。黑種草的精油成分可抑制氣管收縮和增加黏膜纖毛的清除率。
●186位急性咽喉炎測試者,每天3次連續7天服用黑種草油和珠草萃取物,可完全緩解他們的咽喉腫痛,減少對止痛藥的需要。
●抗效喘和擴張氣管
80名哮喘患者的隨機,雙盲,安慰劑對照試驗,每天食用黑種草油兩次,連續4週,NSO組的平均哮喘控制測試得分顯著提高了21.1(標準差= 2.6)和19.6(標準差= 3.7)(p = 0.044),血液中的嗜酸性粒細胞減少了-50 (-155至-1)對15(-60至87)個細胞/μL(p = 0.013)。
29例哮喘成年患者隨機分為對照組和研究組,研究組給予每天口服黑種草提取
物,研究3個月後顯著改善哮喘症狀的頻率/週,胸部喘息和肺功能測試(PFTs)
值顯著改善(P <0.05到P <0.001),與對照組相比有顯著差異(P <0.01到P <0.001)。
在15例哮喘患者,黑種草萃取物對哮喘的氣道(airways)具有相對強效的抗喘效果(支氣管擴張)。
●天然氣管擴張劑,抑制氣管收縮和增加黏膜纖毛的清除2010年歐洲藥用植物和天然產品研究雜誌《Planta Medica》研究:黑種草的精油活性成分-百里醌(TQ) 、黑種草酮(Nigellone)是優於哮喘的吸入性氣管擴張藥fluticasone(屬類固醇類),賦予哮喘和過敏症患者帶來希望。
2008年歐洲藥用植物和天然產品研究雜誌《Planta Medica》研究表明:黑種草油的精油成分黑種草酮(Nigellone)和百里醌(TQ)可用於治療不同的呼吸系統疾病,可緩解氣管的痙攣和增加黏膜纖毛的清除率。
1.Dirjomuljono, M., et al. "Symptomatic treatment of acute tonsillo-pharyngitis patients with a combination of Nigella sativa and Phyllanthus niruriextract." International journal of clinical pharmacology and therapeutics 46.6 (2008): 295-306.
2.Koshak, Abdulrahman, et al. "Nigella sativa supplementation improves asthma control and biomarkers: A randomized, double‐blind, placebo‐controlled trial." PhytotherapyResearch 31.3 (2017): 403-409.
3.Boskabady, Mohammad Hossein, et al. "The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients." Fundamental & clinical pharmacology 21.5 (2007): 559-566.
4.Boskabady, M. H., N. Mohsenpoor, and L. Takaloo. "Antiasthmaticeffect of Nigella sativa in airways of asthmatic patients." Phytomedicine 17.10 (2010): 707-713.
5.Keyhanmanesh, Rana, et al. "The effect of thymoquinone, the main constituent of Nigella sativa on tracheal responsiveness and white blood cell count in lung lavage of sensitized guinea pigs." Planta medica 76.03 (2010): 218-222.
6.Wienkötter, N., et al. "The effect of nigelloneand thymoquinone on inhibiting trachea contraction and mucociliaryclearance." Planta medica 74.02 (2008): 105-108.
#薑黃文獻研究
●#薑黃的薑黃素抑制所有C型肝炎病毒基因型進入人肝細胞
Colpitts, Che C., et al. "Turmeric curcumin inhibits entry of all hepatitis C virusgenotypes into human liver cells." Gut 63.7 (2014): 1137-1149
●#薑黃素在病毒性急性呼吸窘迫綜合症的老鼠模中,調節發炎症反應並抑制隨後的纖維化
Avasarala, Sreedevi, et al. "Curcumin modulates the inflammatory response and inhibits subsequent fibrosis in a mouse model of viral-induced acute respiratory distress syndrome." PloSone 8.2 (2013).
●#薑黃素通過減輕肺損傷和調節巨噬細胞細胞因子產生來減輕嚴重的流感性肺炎
Han, Shuguang, et al. "Curcumin ameliorates severe influenza pneumonia via attenuating lung injury and regulating macrophage cytokines production." Clinical and Experimental. Pharmacology and Physiology 45.1 (2018): 84-93.
#蜂蜜文獻研究
●2014年一項基於前瞻性隊列研究:以蜂蜜做保守療,35%的慢性C型肝炎病毒患者可持續清除C肝炎病毒
KOTB, MAGD A., and AHMED K. ABDALLA. "Sustained Hepatitis C Virus Clearance was Achieved by Honey Based Conservative Management in 35% of Chronic Hepatitis C Virus Patients: A Prospective Cohort Study." Interferon 8: 10.
●蜂蜜與健康:近期臨床研究述評-蜂蜜具抗發炎免疫調節活性、減少咳嗽、發燒和減輕哮喘相關症狀
Samarghandian, Saeed, TaherehFarkhondeh, and FariborzSamini. "Honey and health: A review of recent clinical research." Pharmacognosy research 9.2 (2017): 121.)
#食用建議
#黑種草油5ml + #蜂蜜10ml +#薑黃粉(#或薑黃素)適量
❗每日2次❗
#黑種草油、#蜂蜜和薑黃
都有抗單股RNA病毒、抗發炎、減少肺部發炎症狀,調節免疫力和增加抵抗力的效果,非常適合這個季節做為每日保健的補充劑。
human physiology 在 IELTS Nguyễn Huyền Facebook 的最讚貼文
TỪ VỰNG IELTS ANIMAL TESTING (Kèm ý tưởng)
PHẦN TỪ VỰNG
▪animal testing ≈ animal experimentation: thí nghiệm trên động vật
▪the breeding of genetically modified animals: việc nhân giống động vật biến đổi gen
▪non-animal alternative methods: các phương pháp thay thế phi động vật
▪to undergo safety testing involving animals: trải qua thử nghiệm an toàn sử dụng động vật
▪to replace tests with alternative techniques: thay thế các xét nghiệm bằng các kỹ thuật thay thế
▪to introduce human material into animals: đưa các tế bào/ mô… của con người vào động vật
▪to put human breast tumour cells into mice: đưa tế bào khối u ở người vào chuột
▪to allow researchers to test cancer drugs on human tissue: cho phép các nhà nghiên cứu thử nghiệm thuốc ung thư trên mô người
▪experiment on cell structures instead of whole animals: thí nghiệm trên cấu trúc tế bào thay vì trên toàn bộ cơ thể động vật
▪to use computer models: sử dụng mô hình máy tính
▪study human volunteers: nghiên cứu tình nguyện viên là con người
▪to use epidemiological studies: sử dụng nghiên cứu dịch tễ học
ARGUMENTS FOR ANIMAL TESTING
▪to contribute greatly to scientific advances: đóng góp lớn cho những tiến bộ khoa học
▪to be used to test drugs before they are given to humans: được sử dụng để kiểm tra thuốc trước khi được sử dụng trên đối tượng người
▪to study the effects of genetic diseases: nghiên cứu ảnh hưởng của các bệnh di truyền
▪to find out how genes work: tìm hiểu cách thức hoạt động của gen
▪to explore how organisms function: khám phá cách thức hoạt động của các bộ phận
▪to investigate treatments for human diseases: nghiên cứu các phương pháp điều trị bệnh ở người
▪to be essential in the quest to understand human diseases and ▪to develop new treatments: trở nên thiết yếu trong nỗ lực tìm hiểu các căn bệnh ở người và phát triển các phương pháp điều trị mới
▪advances in the understanding of genetics → animals can be bred with specific genetic traits → allow researchers to explore a range of conditions (cancer, heart disease, stroke, dementia): những tiến bộ trong sự hiểu biết về di truyền → động vật có thể được nhân giống với những đặc điểm di truyền cụ thể → cho phép các nhà nghiên cứu khám phá một loạt các tình trạng bệnh lý (ung thư, bệnh tim, đột quỵ, mất trí nhớ)
▪serious medical or life-saving purposes: những mục đích cứu người và mục đích y tế quan trọng
▪a wealth of medical advances → make with the help of animal research (new vaccines, treatments for cancer, Parkinson’s disease, asthma and HIV): vô số tiến bộ y tế → được thực hiện với sự trợ giúp của nghiên cứu động vật (vắc-xin mới, phương pháp điều trị ung thư, bệnh Parkinson, bệnh hen suyễn và HIV)
ARGUMENTS AGAINST ANIMAL TESTING
▪to cause suffering to animals: gây đau khổ cho động vật
▪cruel, unethical, meaningless/pointless: độc ác, phi đạo đức, vô nghĩa
▪the differences in physiology, genetics and cell structures between animals and humans → invalidate most cures devised by animal experimentation: sự khác biệt về sinh lý, di truyền và cấu trúc tế bào giữa động vật và con người → vô hiệu hóa hầu hết các phương pháp chữa bệnh được tạo ra bởi thí nghiệm trên động vật
▪HIV → deadly to humans but not to most laboratory animals → studying HIV in other species → may not produce results→ applicable to humans: HIV → gây tử vong cho người nhưng không phải với hầu hết các động vật thí nghiệm → nghiên cứu HIV ở các loài khác → có thể không tạo ra kết quả → áp dụng cho người
▪animals do not get many of the human diseases that we do: động vật không mắc nhiều bệnh mà chúng ta đang mắc
▪treatments showing promise in animals → rarely work in humans: phương pháp điều trị hứa hẹn ở động vật → hiếm khi hoạt động trên con người
https://ielts-nguyenhuyen.com/tu-vung-ielts-chu-de-animal-testing/
#ieltsnguyenhuyen
Chúc page mình học tốt nhé <3
human physiology 在 Herman Yeung Youtube 的精選貼文
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HKDSE Mathematics 數學天書 訂購表格及方法︰
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human physiology 在 Herman Yeung Youtube 的最佳解答
Note download 筆記下載 : https://hermanutube.blogspot.hk/2016/01/youtube-pdf.html
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Biology 所有 videos 的 Playlist 可看:
https://www.youtube.com/playlist?list=PLzDe9mOi1K8oSnhUSkuaWV9d7FbyJDSPE
分類的 Playlist 可看:
1. Cells and Molecules of Life 細胞與生命分子… https://www.youtube.com/playlist?list=PLzDe9mOi1K8pimOHKxXgEB4A7BkIU_fvE
2. Genetics and Evolution遺傳與進化… https://www.youtube.com/playlist?list=PLzDe9mOi1K8qxXqviCcE59G2o2S-SZmLz
3A. Essential life processes in plants植物維持生命的活動… https://www.youtube.com/playlist?list=PLzDe9mOi1K8oaLqXiViAOyF-wt_wxD62w
3B. Essential life processes in animals動物維持生命的活動… https://www.youtube.com/playlist?list=PLzDe9mOi1K8petIdjLSGd9BbyfUcDdHim
3C. Reproduction, growth and development生殖、生長和發育... https://www.youtube.com/playlist?list=PLzDe9mOi1K8ramUz1FlN0c8vG47a8qChA
3D. Coordination and response協調和反應… https://www.youtube.com/playlist?list=PLzDe9mOi1K8o6aa0bT1nTs5QbaBpJ69W7
3E. Homeostasis體內平衡… https://www.youtube.com/playlist?list=PLzDe9mOi1K8qIF_r_7bLzL_gbkzL3NRiZ
3F. Ecosystems 生態系… https://www.youtube.com/playlist?list=PLzDe9mOi1K8qHQPt5HmieWo0EjPGnmD81
4. Health and Disease健康與疾病… https://www.youtube.com/playlist?list=PLzDe9mOi1K8oWMLSCZvYm_HxnOCnw0ePt
5. Human Physiology: Regulation and Control人體生理學︰調節與控制… https://www.youtube.com/playlist?list=PLzDe9mOi1K8r0Af7WKwjPf5Ih3hk4rRpw
6. Applied Ecology應用生物學… https://www.youtube.com/playlist?list=PLzDe9mOi1K8rbkiK9KEPGav6_z6otcqA7
7. Microorganisms and Humans微生物與人類… https://www.youtube.com/playlist?list=PLzDe9mOi1K8pA3IcS8sxv5JgWHZ0Ifvrk
8. Biotechnology生物工程… https://www.youtube.com/playlist?list=PLzDe9mOi1K8oNgT2rFFmtFP_PBDbCqn0N
Notes Only Version : https://www.youtube.com/playlist?list=PLzDe9mOi1K8osiwrVWzQRQ9wWCLgZUYS5
Definition 背誦︰
中英對照︰ https://www.youtube.com/playlist?list=PLzDe9mOi1K8pgi_VnjcUHByKdnDfPKfDh
純英版︰ https://www.youtube.com/playlist?list=PLzDe9mOi1K8qhbqCN5tsVn2DeUqYFzYPV
純中版︰ https://www.youtube.com/playlist?list=PLzDe9mOi1K8rAJGqx6SNLcG1WQGTFocOL
HKDSE Biology Past Paper Solution :
https://www.youtube.com/playlist?list=PLzDe9mOi1K8q0icgpscQYKrWcaywLK7g2
HKCEE Biology Past Paper Solution :
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HKALE Biology Past Paper Solution :
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Please subscribe 請訂閱 :
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HKDSE Mathematics 數學天書 訂購表格及方法︰
https://www.sites.google.com/view/HermanYeung
------------------------------------------------------------------------------
Blogger : https://goo.gl/SBmVOO
Facebook : https://www.facebook.com/hy.page
YouTube: https://www.youtube.com/HermanYeung
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human physiology 在 Herman Yeung Youtube 的最佳貼文
Note download 筆記下載 : https://hermanutube.blogspot.hk/2016/01/youtube-pdf.html
------------------------------------------------------------------------------
Biology 所有 videos 的 Playlist 可看:
https://www.youtube.com/playlist?list=PLzDe9mOi1K8oSnhUSkuaWV9d7FbyJDSPE
分類的 Playlist 可看:
1. Cells and Molecules of Life 細胞與生命分子… https://www.youtube.com/playlist?list=PLzDe9mOi1K8pimOHKxXgEB4A7BkIU_fvE
2. Genetics and Evolution遺傳與進化… https://www.youtube.com/playlist?list=PLzDe9mOi1K8qxXqviCcE59G2o2S-SZmLz
3A. Essential life processes in plants植物維持生命的活動… https://www.youtube.com/playlist?list=PLzDe9mOi1K8oaLqXiViAOyF-wt_wxD62w
3B. Essential life processes in animals動物維持生命的活動… https://www.youtube.com/playlist?list=PLzDe9mOi1K8petIdjLSGd9BbyfUcDdHim
3C. Reproduction, growth and development生殖、生長和發育... https://www.youtube.com/playlist?list=PLzDe9mOi1K8ramUz1FlN0c8vG47a8qChA
3D. Coordination and response協調和反應… https://www.youtube.com/playlist?list=PLzDe9mOi1K8o6aa0bT1nTs5QbaBpJ69W7
3E. Homeostasis體內平衡… https://www.youtube.com/playlist?list=PLzDe9mOi1K8qIF_r_7bLzL_gbkzL3NRiZ
3F. Ecosystems 生態系… https://www.youtube.com/playlist?list=PLzDe9mOi1K8qHQPt5HmieWo0EjPGnmD81
4. Health and Disease健康與疾病… https://www.youtube.com/playlist?list=PLzDe9mOi1K8oWMLSCZvYm_HxnOCnw0ePt
5. Human Physiology: Regulation and Control人體生理學︰調節與控制… https://www.youtube.com/playlist?list=PLzDe9mOi1K8r0Af7WKwjPf5Ih3hk4rRpw
6. Applied Ecology應用生物學… https://www.youtube.com/playlist?list=PLzDe9mOi1K8rbkiK9KEPGav6_z6otcqA7
7. Microorganisms and Humans微生物與人類… https://www.youtube.com/playlist?list=PLzDe9mOi1K8pA3IcS8sxv5JgWHZ0Ifvrk
8. Biotechnology生物工程… https://www.youtube.com/playlist?list=PLzDe9mOi1K8oNgT2rFFmtFP_PBDbCqn0N
Notes Only Version : https://www.youtube.com/playlist?list=PLzDe9mOi1K8osiwrVWzQRQ9wWCLgZUYS5
Definition 背誦︰
中英對照︰ https://www.youtube.com/playlist?list=PLzDe9mOi1K8pgi_VnjcUHByKdnDfPKfDh
純英版︰ https://www.youtube.com/playlist?list=PLzDe9mOi1K8qhbqCN5tsVn2DeUqYFzYPV
純中版︰ https://www.youtube.com/playlist?list=PLzDe9mOi1K8rAJGqx6SNLcG1WQGTFocOL
HKDSE Biology Past Paper Solution :
https://www.youtube.com/playlist?list=PLzDe9mOi1K8q0icgpscQYKrWcaywLK7g2
HKCEE Biology Past Paper Solution :
https://www.youtube.com/playlist?list=PLzDe9mOi1K8oE7NKu3W5odiwwws6WerB0
HKALE Biology Past Paper Solution :
https://www.youtube.com/playlist?list=PLzDe9mOi1K8qDsX40O4tczDYBPktC06fq
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Please subscribe 請訂閱 :
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HKDSE Mathematics 數學天書 訂購表格及方法︰
https://www.sites.google.com/view/HermanYeung
------------------------------------------------------------------------------
Blogger : https://goo.gl/SBmVOO
Facebook : https://www.facebook.com/hy.page
YouTube: https://www.youtube.com/HermanYeung
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